Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 3/20 | 0.60 |
| ▸ | ALPI | P09923 | 3/20 | 0.60 |
| ▸ | VCAM1 | P19320 | 14/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11466792 | 0.89 | ALPL (0.62) | ALPLALPIVCAM1APEX1HPGD | |
| SCHEMBL11459161 | 0.86 | ALPL (0.66) | ALPLALPIVCAM1APEX1HPGD | |
| SCHEMBL11456478 | 0.86 | ALPL (0.63) | ALPLALPIVCAM1APEX1HPGD | |
| SCHEMBL7179842 | 0.86 | VCAM1 (0.62) | ALPLALPIVCAM1APEX1NPBWR1 | |
| SCHEMBL11450202 | 0.85 | ALPL (0.54) | ALPLALPIVCAM1SMN1; SMN2NPBWR1 | |
| SCHEMBL11458717 | 0.83 | ALDH1A1 (0.50) | ALPLALPIHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL11458611 | 0.83 | VCAM1 (0.56) | ALPLALPIVCAM1APEX1HPGD | |
| SCHEMBL11458758 | 0.83 | APEX1 (0.61) | ALPLALPIVCAM1APEX1HPGD | |
| SCHEMBL11449140 | 0.83 | ALPL (0.59) | ALPLALPIVCAM1APEX1HPGD | |
| SCHEMBL11449208 | 0.82 | ALPL (0.68) | ALPLALPIVCAM1APEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216161-A | 3,4-Diaminophenyl sulfonic acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-08-05 | — | — | US | disclosed |
| US-3996369-A | Anthelmintically active 2-carbalkoxyamino benzimidazolyl-5(6)-sulfonic acid phenyl esters | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |