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Sugi Predict / Compounds / SCHEMBL1144896

SCHEMBL1144896

SCHEMBL1144896

Cn1cc(C(=O)Nc2c(F)cccc2-c2ccc(F)c(F)c2)c(C(F)F)n1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.42
▸ THRB P10828 1/20 0.42
▸ MAPK1 P28482 9/20 0.40
▸ STIM1 Q13586 1/20 0.39
▸ ORAI1 Q96D31 1/20 0.39
▸ GRM5 P41594 1/20 0.38
▸ DHODH Q02127 5/20 0.38
▸ CHRM3 P20309 1/20 0.38
▸ MAOA P21397 1/20 0.37
▸ MAOB P27338 1/20 0.37
▸ TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16212684 0.91 EGFR (0.40) MAPK1STIM1ORAI1DHODH
SCHEMBL1145148 0.91 CHRNA7 (0.43) MAPK1STIM1ORAI1DHODHCHRM3
SCHEMBL868026 0.89 EGFR (0.40) MAPK1STIM1ORAI1DHODH
SCHEMBL3685890 0.88 HTT (0.43) STIM1ORAI1GRM5DHODHTP53
SCHEMBL16972354 0.87 CHRM3 (0.39) MAPTTHRBMAPK1CHRM3
SCHEMBL4793286 0.86 CHRM3 (0.48) MAPTTHRBCHRM3TP53
SCHEMBL1134823 0.84 LMNA (0.53) MAPTTHRBMAPK1DHODH
SCHEMBL29445397 0.84 LMNA (0.53) MAPTTHRBMAPK1DHODH
SCHEMBL4477674 0.83 CHRNA7 (0.42) MAPK1DHODHCHRM3MAOAMAOB
SCHEMBL4921015 0.83 CSNK1D (0.39) MAPTTHRBMAPK1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150257387-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2015-09-17 — — US claimed
EP-2285779-B1 Method for manufacturing aryl carboxamides BASF SE (DE) 2013-03-27 — — EP claimed
US-8350046-B2 Method for manufacturing aryl carboxamides BASF SE (DE) 2013-01-08 — — US claimed
EP-2395833-A1 DIMETHOMORPH AS SAFENER FOR PESTICIDES WITH PHYTOTOXIC EFFECTS BASF SE (DE) 2011-12-21 — — EP claimed
US-20110054183-A1 Method For Manufacturing Aryl Carboxamides BASF SE 2011-03-03 — — US claimed
WO-2010092119-A1 DIMETHOMORPH AS SAFENER FOR PESTICIDES WITH PHYTOTOXIC EFFECTS BASF SE (DE) 2010-08-19 — — WO claimed
US-20100197741-A1 Ternary Fungicidal Compositions Comprising Boscalid and Chlorothalonil BASF SE (DE) 2010-08-05 — — US claimed
US-20100048403-A1 Method of inducing virus tolerance of plants BASF SE (DE) 2010-02-25 — — US claimed
US-20100035753-A1 Fungicidal Mixtures Comprising Substituted 1-methylpyrazol-4-ylcarboxanilides BASF SE (DE) 2010-02-11 — — US claimed
EP-2109362-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2009-10-21 — — EP claimed
EP-2061320-A2 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES BASF SE (DE) 2009-05-27 — — EP claimed
WO-2008098928-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2008-08-21 — — WO claimed
WO-2008095890-A2 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES BASF SE (DE) 2008-08-14 — — WO claimed
US-12336537-B2 Fungicidal compositions SYNGENTA CROP PROTECTION AG (CH) 2025-06-24 — — US disclosed
CN-114586791-B Sterilization composition containing fluxapyroxad and application thereof 青岛恒宁生物科技有限公司 2024-03-08 — — CN disclosed
CN-117285427-A Preparation method of fluxapyroxad intermediate 3',4',5' -trifluoro biphenyl-2-amine 山东京博农化科技股份有限公司 2023-12-26 — — CN disclosed
WO-2008152096-A2 USE OF FUNGICIDES FOR MAKING THE PHENOLOGICAL DEVELOPMENT OF OIL PLANTS MORE COHERENT BASF SE (DE) 2008-12-18 — — WO disclosed
WO-2008152138-A2 METHOD FOR PRODUCING DIFLUOROMETHYL-SUBSTITUTED PYRAZOLE COMPOUNDS BASF SE (DE) 2008-12-18 — — WO disclosed
WO-2008098928-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2008-08-21 — — WO disclosed
WO-2008095890-A2 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES BASF SE (DE) 2008-08-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054183-A1 Method For Manufacturing Aryl Carboxamides H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR3, CBR1 MAPT 4741/4885THRB 2747/4885MAPK1 1742/4885
US-20150257387-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 MAPT 557/4885THRB 1173/4885MAPK1 4598/4885
US-20100197741-A1 Ternary Fungicidal Compositions Comprising Boscalid and Chlorothalonil CBR3, CBX3, BRD3 MAPT 3070/4885THRB 4684/4885MAPK1 4275/4885
US-20100048403-A1 Method of inducing virus tolerance of plants CBR3, CBR1, CYC1 MAPT 3350/4885THRB 3552/4885MAPK1 2683/4885
US-20100035753-A1 Fungicidal Mixtures Comprising Substituted 1-methylpyrazol-4-ylcarboxanilides CBR3, CBR1, HCN2 MAPT 4747/4885THRB 4163/4885MAPK1 2782/4885
US-12336537-B2 Fungicidal compositions CYP51A1, CYP4X1, CYP1B1 MAPT 2069/4885THRB 3247/4885MAPK1 3559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.