Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 7/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145148 | 0.92 | CHRNA7 (0.43) | CHRNA7EGFRCHRM3MAPK1MAOA | |
| SCHEMBL868026 | 0.87 | EGFR (0.40) | CHRNA7EGFRMAPK1DHODH | |
| SCHEMBL16212684 | 0.85 | EGFR (0.40) | CHRNA7EGFRMAPK1DHODH | |
| SCHEMBL13006486 | 0.84 | LMNA (0.55) | CHRNA7EGFRMAPK1DHODH | |
| SCHEMBL1144896 | 0.83 | MAPT (0.42) | CHRM3MAPK1MAOAMAOBDHODH | |
| SCHEMBL3385594 | 0.82 | CHRNA7 (0.41) | CHRNA7EGFRCHRM3MAPK1MAOA | |
| SCHEMBL4477671 | 0.81 | LMNA (0.45) | CHRNA7EGFRCHRM3MAOAMAOB | |
| SCHEMBL4918770 | 0.79 | CHRM3 (0.50) | CHRM3MAPK1MAOAMAOBCHRM1 | |
| SCHEMBL4455890 | 0.79 | ATM (0.46) | EGFRDHODH | |
| SCHEMBL1145119 | 0.78 | LMNA (0.53) | EGFRMAPK1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521397-B2 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2009-04-21 | — | — | US | disclosed |
| US-7329633-B2 | Disubstituted pyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-17 | — | — | US | disclosed |
| US-20060116414-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116414-A1 | Disubstituted pyrazolyl carboxanilides | MRPL21, RRS1, CBR3 | CHRNA7 3475/4885EGFR 1726/4885CHRM3 412/4885 |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | MRPL21, CBR3, CBR1 | CHRNA7 3399/4885EGFR 1769/4885CHRM3 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.