SCHEMBL868026

SCHEMBL868026

Cn1cc(C(=O)Nc2c(F)cccc2-c2ccc(Cl)c(Cl)c2)c(C(F)F)n1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.40
DHODH Q02127 9/20 0.39
SCN9A Q15858 1/20 0.39
ABL1 P00519 1/20 0.38
STIM1 Q13586 1/20 0.38
ORAI1 Q96D31 1/20 0.38
RORC P51449 1/20 0.38
EIF4E P06730 1/20 0.38
GAA P10253 1/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CHRNA7 P36544 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1145148 0.94 CHRNA7 (0.43) EGFRDHODHSTIM1ORAI1CHRNA7
SCHEMBL16212684 0.94 EGFR (0.40) EGFRDHODHSTIM1ORAI1RORC
SCHEMBL1144896 0.89 MAPT (0.42) DHODHSTIM1ORAI1MAPK1
SCHEMBL4477674 0.87 CHRNA7 (0.42) EGFRDHODHCHRNA7MAPK1
SCHEMBL567351 0.86 CHRM3 (0.47) HTT
SCHEMBL3685890 0.86 HTT (0.43) DHODHSTIM1ORAI1HTT
SCHEMBL1145119 0.85 LMNA (0.53) EGFRDHODHMAPK1
SCHEMBL4920641 0.85 CHRM3 (0.39) SCN9AGAAHTTNPSR1SMN1; SMN2
SCHEMBL972255 0.84 EGFR (0.48) EGFRDHODHSMN1; SMN2
SCHEMBL68043 0.81 CHRM3 (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 EP claimed
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 US claimed
WO-2020206518-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS AGRIVALLE BRASIL INDUSTRIA E COMÉRCIO DE PRODUTOS AGRÍCOLAS LTDA (BR) 2020-10-15 WO claimed
EP-3240406-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION (US) 2017-11-08 EP claimed
EP-3240421-A1 MICROBIAL COMPOSITIONS FOR USE IN COMBINATION WITH SOIL INSECTICIDES FOR BENEFITING PLANT GROWTH FMC Corporation (US) 2017-11-08 EP claimed
US-20170215418-A1 Controlling Red Rice with Mesotrione FMC CORP (US) 2017-08-03 US claimed
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2017-07-13 US claimed
US-9635854-B2 Controlling red rice with mesotrione FMC CORPORATION (US) 2017-05-02 US claimed
US-9622484-B2 Microbial compositions and methods of use for benefiting plant growth and treating plant disease FMC CORPORATION (US) 2017-04-18 US claimed
US-9439435-B2 Method for controlling weeds using formulations containing fluthiacet-methyl and HPPD herbicides FMC CORPORATION (US) 2016-09-13 US claimed
US-20110054183-A1 Method For Manufacturing Aryl Carboxamides BASF SE 2011-03-03 US claimed
US-20100197741-A1 Ternary Fungicidal Compositions Comprising Boscalid and Chlorothalonil BASF SE (DE) 2010-08-05 US claimed
EP-2205082-A1 TERNARY FUNGICIDAL COMPOSITIONS COMPRISING BOSCALID AND CHLOROTHALONIL BASF SE (DE) 2010-07-14 EP claimed
US-20100048403-A1 Method of inducing virus tolerance of plants BASF SE (DE) 2010-02-25 US claimed
US-20100035753-A1 Fungicidal Mixtures Comprising Substituted 1-methylpyrazol-4-ylcarboxanilides BASF SE (DE) 2010-02-11 US claimed
EP-2109362-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2009-10-21 EP claimed
EP-2061320-A2 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES BASF SE (DE) 2009-05-27 EP claimed
WO-2009040397-A1 TERNARY FUNGICIDAL COMPOSITIONS COMPRISING BOSCALID AND CHLOROTHALONIL BASF SE (DE) 2009-04-02 WO claimed
WO-2008098928-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2008-08-21 WO claimed
WO-2008095890-A2 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES BASF SE (DE) 2008-08-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054183-A1 Method For Manufacturing Aryl Carboxamides H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR3, CBR1 EGFR 869/4885DHODH 2901/4885SCN9A 2961/4885
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC EGFR 2599/4885DHODH 2182/4885SCN9A 4753/4885
US-20100197741-A1 Ternary Fungicidal Compositions Comprising Boscalid and Chlorothalonil CBR3, CBX3, BRD3 EGFR 3944/4885DHODH 3316/4885SCN9A 2511/4885
US-20100048403-A1 Method of inducing virus tolerance of plants CBR3, CBR1, CYC1 EGFR 1834/4885DHODH 3301/4885SCN9A 2952/4885
US-20100035753-A1 Fungicidal Mixtures Comprising Substituted 1-methylpyrazol-4-ylcarboxanilides CBR3, CBR1, HCN2 EGFR 2528/4885DHODH 3445/4885SCN9A 843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.