Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11449182 | 0.87 | HRH3 (0.31) | HRH3MAPK1 | |
| SCHEMBL7270417 | 0.85 | CTSC (0.36) | MAPK1 | |
| SCHEMBL25930148 | 0.85 | CTSC (0.36) | MAPK1 | |
| SCHEMBL11449581 | 0.82 | CHRNB2 (0.36) | — | |
| SCHEMBL15248182 | 0.82 | CHRNB2 (0.36) | — | |
| SCHEMBL9949501 | 0.79 | CHRM2 (0.41) | HRH3MAPK1 | |
| SCHEMBL11448891 | 0.79 | HRH3 (0.32) | HRH3MAPK1 | |
| SCHEMBL9949495 | 0.79 | CHRM2 (0.41) | HRH3MAPK1 | |
| SCHEMBL7885453 | 0.79 | CHRNB2 (0.39) | HRH3 | |
| SCHEMBL584184 | 0.79 | CHRNB2 (0.39) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221912-A | Dithio derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1980-09-09 | — | — | US | disclosed |
| US-4217458-A | Acylmercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4198515-A | Mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1980-04-15 | — | — | US | disclosed |