Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073129 | 0.85 | PARP1 (0.55) | TLR7CYP1A2PARP1ALDH1A1HPGD | |
| SCHEMBL11440934 | 0.85 | TLR7 (0.49) | TLR7ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11290683 | 0.84 | GRIK2 (0.47) | TLR7CYP1A2CYP1A1CYP1B1HPGD | |
| SCHEMBL11076059 | 0.83 | TLR7 (0.48) | TLR7CYP1A2PARP1ALDH1A1HPGD | |
| SCHEMBL11436977 | 0.83 | MAOB (0.48) | TLR7CYP1A2CYP1A1MAPTADORA2A | |
| SCHEMBL11448810 | 0.82 | SHMT2 (0.48) | ALDH1A1HPGDKMT2AHSD17B10KDM4E | |
| SCHEMBL11075432 | 0.82 | SHMT2 (0.48) | TLR7PARP1ALDH1A1HPGDKMT2A | |
| SCHEMBL9611690 | 0.82 | TLR7 (0.61) | TLR7ALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL11449199 | 0.82 | TLR7 (0.46) | TLR7CYP1A2CYP1A1CYP1B1KMT2A | |
| SCHEMBL11443172 | 0.79 | TLR7 (0.45) | TLR7CYP1A2ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012866-B1 | NEW 3H-NAPHTHO(1,2-D)IMIDAZOLES, PROCESSES FOR PREPARING THEM, COMPOUNDS FOR USE AS ANTIINFLAMMATORY AND ANTIMICROBIAL AGENTS AND COMPOSITIONS FOR THAT USE CONTAINING THEM | GRUPPO LEPETIT S.P.A. (IT) | 1983-01-19 | — | — | EP | disclosed |
| US-4340607-A | Antimicrobial 3H-naphtho[1,2-d]imidazoles | GRUPPO LEPETIT S.P.A. (IT) | 1982-07-20 | — | — | US | disclosed |