Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | APEX1 | P27695 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | RGS12 | O14924 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12125341 | 0.82 | HPGD (0.66) | ALDH1A1GAATSHRTDP1NFKB1 | |
| SCHEMBL25446709 | 0.82 | PRKCE (0.47) | ALDH1A1TSHRTDP1HPGDHSD17B10 | |
| SCHEMBL10825727 | 0.82 | GAA (0.70) | ALDH1A1GAATSHRTDP1NFKB1 | |
| SCHEMBL24410610 | 0.82 | GAA (0.47) | ALDH1A1GAATSHRTDP1NFKB1 | |
| SCHEMBL6559232 | 0.79 | HPGD (0.61) | ALDH1A1GAATSHRTDP1NFKB1 | |
| SCHEMBL28641995 | 0.79 | TRPA1 (0.55) | ALDH1A1TDP1HPGDHSD17B10KDM4E | |
| SCHEMBL25460973 | 0.79 | PRKCE (0.44) | ALDH1A1TSHRTDP1HPGDHSD17B10 | |
| SCHEMBL13449226 | 0.78 | ALDH1A1 (0.44) | ALDH1A1GAATSHRTDP1NFKB1 | |
| SCHEMBL11395073 | 0.77 | GAA (0.63) | ALDH1A1GAATSHRTDP1NFKB1 | |
| SCHEMBL2623695 | 0.77 | GAA (0.63) | ALDH1A1GAATSHRTDP1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4197240-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1980-04-08 | — | — | US | disclosed |