Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 3/20 | 0.56 |
| ▸ | ALPI | P09923 | 3/20 | 0.56 |
| ▸ | VCAM1 | P19320 | 11/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11456478 | 0.88 | ALPL (0.63) | ALPLALPIVCAM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11448255 | 0.87 | ALPL (0.59) | ALPLALPIVCAM1CYP1A2CYP3A4 | |
| SCHEMBL11450417 | 0.87 | CYP1A2 (0.61) | ALPLALPIVCAM1CYP1A2CYP3A4 | |
| SCHEMBL11449495 | 0.86 | ALPL (0.53) | ALPLALPIVCAM1CYP1A2CYP3A4 | |
| SCHEMBL7179842 | 0.85 | VCAM1 (0.62) | ALPLALPIVCAM1 | |
| SCHEMBL11449191 | 0.85 | ALDH1A1 (0.50) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11450202 | 0.85 | ALPL (0.54) | ALPLALPIVCAM1CYP1A2CYP3A4 | |
| SCHEMBL11665975 | 0.84 | APEX1 (0.60) | ALPLALPINFE2L2CYP1A2CYP3A4 | |
| SCHEMBL11449208 | 0.82 | ALPL (0.68) | ALPLALPIVCAM1ALDH1A1 | |
| SCHEMBL11317864 | 0.81 | ALPL (0.51) | ALPLALPIVCAM1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216161-A | 3,4-Diaminophenyl sulfonic acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-08-05 | — | — | US | disclosed |
| US-4069325-A | 3-Carbalkoxyamino-1H-2,1,4-benzothiadiazine derivatives | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-17 | — | — | US | disclosed |
| US-3996369-A | Anthelmintically active 2-carbalkoxyamino benzimidazolyl-5(6)-sulfonic acid phenyl esters | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |