Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | DBH | P09172 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | BAX | Q07812 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23263221 | 0.86 | ALDH1A1 (0.47) | LMNADBHHDAC4HDAC2HDAC8 | |
| SCHEMBL2916124 | 0.82 | LTA4H (0.52) | CTNNB1KMT2ALMNAGAALTA4H | |
| SCHEMBL9768120 | 0.80 | LTA4H (0.55) | CTNNB1KMT2ALMNAGAALTA4H | |
| SCHEMBL396882 | 0.78 | ALDH1A1 (0.52) | CTNNB1KMT2ALMNAGAALTA4H | |
| SCHEMBL11615272 | 0.78 | MAOB (0.46) | CTNNB1KMT2ALMNAGAAHDAC6 | |
| SCHEMBL23263220 | 0.76 | GAA (0.44) | CTNNB1KMT2ALMNAGAATTR | |
| SCHEMBL11441965 | 0.75 | ADORA2A (0.53) | CTNNB1KMT2ALMNAGAALTA4H | |
| SCHEMBL5693313 | 0.74 | MAPT (0.58) | KMT2ALMNAGAADBHHDAC4 | |
| SCHEMBL51822 | 0.74 | LTA4H (0.69) | CTNNB1KMT2ALMNAGAALTA4H | |
| SCHEMBL7738229 | 0.73 | L3MBTL1 (0.47) | CTNNB1KMT2ALMNAGAALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4183955-A | Troponyl-oxamic acid derivatives for treating allergic conditions | Ayerst. McKenna & Harrison Limited (CA) | 1980-01-15 | — | — | US | disclosed |
| US-4125625-A | ANTIALLERGENS | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-11-14 | — | — | US | disclosed |
| US-4057556-A | ANTIALLERGENS | AYERST, MCKENNA & HARRISON LTD. (CA) | 1977-11-08 | — | — | US | disclosed |