Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10856015 | 0.98 | ALDH1A1 (0.55) | GAATSHRCASP1ALDH1A1POLB | |
| SCHEMBL11049965 | 0.98 | SMN1; SMN2 (0.53) | GAATSHRCASP1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL10856957 | 0.97 | ALDH1A1 (0.54) | GAATSHRCASP1ALDH1A1POLB | |
| SCHEMBL10860457 | 0.96 | ALDH1A1 (0.54) | GAATSHRCASP1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL10858250 | 0.95 | ALDH1A1 (0.52) | GAATSHRCASP1ALDH1A1POLB | |
| Perchlorate SCHEMBL10863084 | 0.89 | ALDH1A1 (0.48) | GAATSHRCASP1ALDH1A1POLB | |
| SCHEMBL17624388 | 0.72 | MTHFD2 (0.48) | GAATSHRCASP1ALDH1A1POLB | |
| Benzene SCHEMBL11192509 | 0.70 | MEN1 (0.46) | GAATSHRCASP1ALDH1A1POLB | |
| SCHEMBL2953501 | 0.69 | ALDH1A1 (1.00) | GAATSHRCASP1ALDH1A1POLB | |
| SCHEMBL10613505 | 0.69 | ALDH1A1 (0.49) | GAAALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4220771-A | MORPHINE POTENTIATORS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1980-09-02 | — | — | US | disclosed |