Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11493600 | 0.81 | GRM2 (0.37) | ALDH1A1 | |
| SCHEMBL3414493 | 0.78 | LMNA (0.34) | APLNR | |
| SCHEMBL3382623 | 0.74 | ALDH1A1 (0.33) | ALDH1A1APLNR | |
| SCHEMBL11442383 | 0.73 | HTT (0.32) | APLNR | |
| SCHEMBL10885916 | 0.72 | PPP5C (0.39) | TSHRALDH1A1 | |
| SCHEMBL11469644 | 0.72 | PPP5C (0.39) | TSHRALDH1A1 | |
| SCHEMBL11494572 | 0.72 | ALDH1A1 (0.35) | ALDH1A1APLNR | |
| SCHEMBL11082163 | 0.70 | GBA1 (0.39) | TSHRALDH1A1 | |
| SCHEMBL11444377 | 0.70 | — | — | |
| SCHEMBL11203554 | 0.70 | APLNR (0.37) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238614-A | Pyridyl esters of ether and thioether substituted cyclopropanecarboxylic acids | ZOECON CORPORATION (US) | 1980-12-09 | — | — | US | disclosed |
| US-4229352-A | Benzylpyrrolylmethyl esters of cyclopropane carboxylic acids | ZOECON CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4225533-A | Fluorobenzyl esters of cyclopropanecarboxylic acids | ZOECON CORPORATION (US) | 1980-09-30 | — | — | US | disclosed |