Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333570 | 0.80 | ALDH1A1 (0.56) | KMT2AALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL9419434 | 0.72 | AKR1C4 (0.47) | KMT2AALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL20639027 | 0.71 | ALDH1A1 (0.41) | KMT2AALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL11453246 | 0.68 | SMN1; SMN2 (0.44) | KMT2AALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL11452007 | 0.67 | ALDH1A1 (0.32) | ALDH1A1TSHRALOX15POLB | |
| SCHEMBL3233109 | 0.67 | ERN1 (0.47) | KMT2AALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL11452025 | 0.67 | ALDH1A1 (0.36) | KMT2AALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL111202 | 0.66 | AKR1C4 (0.54) | KMT2AALDH1A1HSD17B10TSHRCYP3A4 | |
| SCHEMBL3758626 | 0.66 | ALDH1A1 (0.46) | KMT2AALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL2093961 | 0.64 | KMT2A (0.44) | KMT2AALDH1A1HSD17B10TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190663-A | Anti-thrombotic 1,2-benzisothiazolin-3-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-26 | — | — | US | disclosed |
| US-4156729-A | ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |