Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769572 | 0.86 | TSHR (0.45) | SMN1; SMN2TSHRCASP1MAPTKDM4E | |
| SCHEMBL6070125 | 0.84 | ALDH1A1 (0.44) | SMN1; SMN2TSHRCASP1MAPTKDM4E | |
| SCHEMBL8607500 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRCASP1MAPTKDM4E | |
| SCHEMBL11463582 | 0.78 | MEN1 (0.39) | SMN1; SMN2MAPTALDH1A1HPGDMEN1 | |
| SCHEMBL11470770 | 0.78 | PTPRC (0.40) | SMN1; SMN2CASP1MAPTKDM4EALDH1A1 | |
| SCHEMBL11095215 | 0.78 | TSHR (0.39) | SMN1; SMN2TSHRCASP1MAPTKDM4E | |
| SCHEMBL4071201 | 0.78 | ABL1 (0.60) | SMN1; SMN2CASP1MAPTKDM4EALDH1A1 | |
| SCHEMBL11706200 | 0.77 | PDE7A (0.49) | SMN1; SMN2TSHRCASP1ALDH1A1HPGD | |
| SCHEMBL654794 | 0.76 | ALDH1A1 (0.52) | SMN1; SMN2TSHRCASP1MAPTKDM4E | |
| SCHEMBL11452007 | 0.75 | ALDH1A1 (0.32) | TSHRALDH1A1ALOX15POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190663-A | Anti-thrombotic 1,2-benzisothiazolin-3-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-26 | — | — | US | disclosed |
| US-4156729-A | ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |