Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GALK1 | P51570 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335636 | 0.78 | MAPT (0.35) | MAPTHTTSMN1; SMN2TP53STAT3 | |
| SCHEMBL3373305 | 0.69 | LMNA (0.32) | MAPTHTTCYP1A2KMT2ALMNA | |
| SCHEMBL11127445 | 0.69 | GAA (0.31) | MAPTSMN1; SMN2LMNAGAA | |
| Hydrochloric Acid SCHEMBL11127443 | 0.68 | LMNA (0.32) | LMNA | |
| Hydrochloric Acid SCHEMBL9499855 | 0.67 | LMNA (0.31) | LMNA | |
| SCHEMBL5170761 | 0.65 | MAPT (0.37) | MAPTHTTSMN1; SMN2TP53STAT3 | |
| SCHEMBL10654038 | 0.65 | — | — | |
| SCHEMBL3373377 | 0.62 | — | — | |
| SCHEMBL11140451 | 0.62 | SMN1; SMN2 (0.39) | MAPTHTTSMN1; SMN2TP53CYP1A2 | |
| SCHEMBL10435911 | 0.61 | MAPT (0.36) | MAPTHTTSMN1; SMN2TP53STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225662-A | 5-(ACETOACETAMIDO)BENZIMIDAZOLIN-2-ONE YELLOW COUPLERS | RICOH COMPANY, LTD. (JP) | 1980-09-30 | — | — | US | disclosed |