Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615927 | 0.81 | KDM4E (0.47) | PPARGPPARAKDM4EMRGPRX4ALDH1A1 | |
| SCHEMBL19750630 | 0.80 | KDM4E (0.56) | KDM4EMRGPRX4ALDH1A1GAA | |
| SCHEMBL4046553 | 0.80 | KDM4E (0.56) | KDM4EMRGPRX4ALDH1A1GAA | |
| SCHEMBL29847359 | 0.80 | KDM4E (0.56) | KDM4EMRGPRX4ALDH1A1GAA | |
| SCHEMBL817445 | 0.79 | TSHR (0.60) | PPARGPPARAKDM4EMRGPRX4ALDH1A1 | |
| SCHEMBL16414719 | 0.79 | TSHR (0.60) | PPARGPPARAKDM4EMRGPRX4ALDH1A1 | |
| SCHEMBL16414613 | 0.79 | TSHR (0.60) | PPARGPPARAKDM4EMRGPRX4ALDH1A1 | |
| SCHEMBL4047162 | 0.79 | L3MBTL1 (0.54) | KDM4EMRGPRX4ALDH1A1GAA | |
| SCHEMBL585546 | 0.78 | KDM4E (0.68) | PPARGPPARAKDM4EMRGPRX4ALDH1A1 | |
| SCHEMBL31645913 | 0.78 | KDM4E (0.68) | PPARGPPARAKDM4EMRGPRX4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4189606-A | ABOSTIFACIENT | GRUPPO LEPETIT S.P.A. (IT) | 1980-02-19 | — | — | US | disclosed |
| US-4182903-A | ABOSTIFACIENTS | GRUPPO LEPETIT S.P.A. (IT) | 1980-01-08 | — | — | US | disclosed |