Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10997019 | 0.76 | KMT2A (0.42) | ALDH1A1MAPK1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL11832759 | 0.74 | SMN1; SMN2 (0.51) | ALDH1A1MAPK1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL14078325 | 0.71 | ALDH1A1 (0.37) | ALDH1A1MAPK1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL11452007 | 0.71 | ALDH1A1 (0.32) | ALDH1A1POLB | |
| SCHEMBL11375094 | 0.70 | LMNA (0.51) | ALDH1A1MAPK1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL11454006 | 0.69 | KDM4E (0.31) | ALDH1A1KDM4EGAA | |
| SCHEMBL11470639 | 0.69 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2ANPC1KDM4E | |
| SCHEMBL6593403 | 0.69 | MAPT (0.56) | ALDH1A1MAPK1RAB9AMEN1KMT2A | |
| SCHEMBL8939314 | 0.68 | HTT (0.39) | ALDH1A1MAPK1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL7370339 | 0.68 | ALDH1A1 (0.57) | ALDH1A1MAPK1SMN1; SMN2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190663-A | Anti-thrombotic 1,2-benzisothiazolin-3-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-26 | — | — | US | disclosed |
| US-4156729-A | ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |