Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472381 | 0.84 | ALDH1A1 (0.48) | KMT2ARAB9AMAPK1HPGDALOX15 | |
| SCHEMBL27390221 | 0.84 | KMT2A (0.42) | KMT2ARAB9AMAPK1HPGDALOX15 | |
| SCHEMBL11832759 | 0.78 | SMN1; SMN2 (0.51) | KMT2ARAB9AMAPK1HPGDCYP1A2 | |
| SCHEMBL10914144 | 0.78 | RAB9A (0.40) | KMT2ARAB9AMAPK1HPGDALOX15 | |
| SCHEMBL14078325 | 0.76 | ALDH1A1 (0.37) | KMT2ARAB9AMAPK1HPGDCYP1A2 | |
| SCHEMBL11451990 | 0.76 | ALDH1A1 (0.37) | KMT2ARAB9AMAPK1HPGDCYP1A2 | |
| SCHEMBL4771857 | 0.75 | MAPK1 (0.40) | KMT2ARAB9AMAPK1HPGDALOX15 | |
| SCHEMBL5302174 | 0.75 | AHR (0.53) | KMT2ARAB9AMAPK1HPGDCYP3A4 | |
| SCHEMBL30787730 | 0.75 | AHR (0.53) | KMT2ARAB9AMAPK1HPGDCYP3A4 | |
| SCHEMBL101268 | 0.75 | TSHR (0.42) | KMT2AMAPK1HPGDALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134485-A2 | 5-Cyclopropyl-5,8-dihydro-8-oxo-1,3-dioxolo-(4,5-g) quinoline-7-carboxylic acid, process for its preparation and bactericidal agent containing it | BAYER AG (DE) | 1985-03-20 | — | — | EP | claimed |
| EP-0134485-A2 | 5-Cyclopropyl-5,8-dihydro-8-oxo-1,3-dioxolo-(4,5-g) quinoline-7-carboxylic acid, process for its preparation and bactericidal agent containing it | BAYER AG (DE) | 1985-03-20 | — | — | EP | disclosed |