Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.75 |
| ▸ | HPGD | P15428 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 4/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11452241 | 0.87 | ABCC1 (0.74) | KDM4EALDH1A1LMNAGAAHPGD | |
| SCHEMBL11524111 | 0.87 | KDM4E (0.81) | KDM4EALDH1A1LMNAGAAHPGD | |
| SCHEMBL11452070 | 0.87 | ADORA3 (0.67) | KDM4EALDH1A1LMNAGAAHPGD | |
| SCHEMBL11470832 | 0.87 | CACNA1D (0.59) | KDM4EALDH1A1LMNAGAAHPGD | |
| SCHEMBL7814802 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1LMNAGAAHPGD | |
| SCHEMBL11452254 | 0.80 | DHFR (0.55) | KDM4EALDH1A1LMNAGAAHPGD | |
| SCHEMBL11461893 | 0.79 | CACNA1B (0.53) | KDM4EALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL11459111 | 0.79 | ABCC1 (0.55) | KDM4EALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL7817206 | 0.78 | KDM4E (0.88) | KDM4EALDH1A1LMNAGAAHPGD | |
| SCHEMBL11735441 | 0.77 | KDM4E (0.60) | KDM4EALDH1A1LMNAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188395-A | 1,4-Dihydropyridine derivatives substituted in the 2 position, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-12 | — | — | US | disclosed |