SCHEMBL7814802

SCHEMBL7814802

CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccc(OC)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 1.00
ALDH1A1 P00352 3/20 1.00
LMNA P02545 1/20 1.00
GAA P10253 1/20 1.00
HPGD P15428 1/20 1.00
HSD17B10 Q99714 1/20 1.00
TSHR P16473 1/20 0.74
SMN1; SMN2 Q16637 1/20 0.74
ABCC1 P33527 1/20 0.72
ADORA3 P0DMS8 2/20 0.68
HRH3 Q9Y5N1 5/20 0.60
CACNA1D Q01668 4/20 0.59
NPSR1 Q6W5P4 1/20 0.59
BCHE P06276 4/20 0.59
CACNA1F O60840 3/20 0.59
CACNA1S Q13698 3/20 0.59
CACNA1C Q13936 3/20 0.59
ACHE P22303 2/20 0.57
HRH4 Q9H3N8 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7817206 0.91 KDM4E (0.88) KDM4EALDH1A1LMNAGAAHPGD
SCHEMBL11524111 0.90 KDM4E (0.81) KDM4EALDH1A1LMNAGAAHPGD
SCHEMBL15989536 0.88 KDM4E (0.79) KDM4EALDH1A1LMNAGAAHPGD
SCHEMBL11372026 0.86 LMNA (0.75) KDM4EALDH1A1LMNAGAAHPGD
SCHEMBL11451997 0.86 KDM4E (0.75) KDM4EALDH1A1LMNAGAAHPGD
SCHEMBL11817128 0.86 KDM4E (0.76) KDM4EALDH1A1LMNAGAAHPGD
SCHEMBL3032293 0.86 KDM4E (0.80) KDM4EALDH1A1LMNAGAAHPGD
SCHEMBL10479276 0.85 ALDH1A1 (0.73) KDM4EALDH1A1LMNAGAAHPGD
SCHEMBL11819175 0.85 KDM4E (0.74) KDM4EALDH1A1LMNAGAAHPGD
SCHEMBL7368284 0.85 KDM4E (1.00) KDM4EALDH1A1LMNAGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119819362-A Photocatalyst for efficiently catalyzing and synthesizing halogenated aromatic hydrocarbon as well as preparation method and application thereof 中国石油大学(华东) 2025-04-15 CN claimed
CN-119819362-A Photocatalyst for efficiently catalyzing and synthesizing halogenated aromatic hydrocarbon as well as preparation method and application thereof 中国石油大学(华东) 2025-04-15 CN disclosed
CN-110483563-B Preparation method and application of novel ionic beta-naphthoic aldehyde Schiff base zirconium complex 山西医科大学 2021-12-28 CN disclosed
CN-110683984-A Method for ultrasonically oxidizing hanster 1, 4-dihydropyridine derivative 阜阳师范大学 2020-01-14 CN disclosed
US-6265127-B1 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers EASTMAN KODAK COMPANY 2001-07-24 US disclosed
EP-1109070-A2 1,4-Dihydropyridine charge control agents for electrostatographic toners and developers EASTMAN KODAK COMPANY (US) 2001-06-20 EP disclosed