Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CPN1 | P15169 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL1257513 | 0.86 | TP53 (0.50) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL27745084 | 0.84 | MEN1 (0.46) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL16445982 | 0.84 | MEN1 (0.46) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Methylmalonic Acid SCHEMBL5874885 | 0.83 | TP53 (0.40) | TP53CPN1CPB2SMN1; SMN2GABRP | |
| Methylmalonic Acid SCHEMBL5874895 | 0.83 | TP53 (0.40) | TP53CPN1CPB2SMN1; SMN2GABRP | |
| Morpholine SCHEMBL219044 | 0.80 | KMT2A (0.58) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL29207396 | 0.80 | KMT2A (0.58) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL11524539 | 0.80 | MEN1 (0.65) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL4018377 | 0.80 | MEN1 (0.65) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL14957611 | 0.80 | MEN1 (0.65) | MEN1KMT2AKDM4EGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4232152-A | POLYURETHANE CATALYSTS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4223139-A | CATALYSTS FOR POLYURETHANE SYNTHESIS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1980-09-16 | — | — | US | disclosed |
| US-4204062-A | CATALYSTS FOR POLYURETHANE SYNTHESIS | AIR PRODUCTS & CHEMICALS, INC. (US) | 1980-05-20 | — | — | US | disclosed |