Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ACHE | P22303 | 4/20 | 0.61 |
| ▸ | BACE1 | P56817 | 3/20 | 0.61 |
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | CCR5 | P51681 | 2/20 | 0.55 |
| ▸ | DRD4 | P21917 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | CCR3 | P51677 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17432875 | 0.92 | MEN1 (0.61) | POLBLMNAMEN1KMT2AACHE | |
| SCHEMBL1002852 | 0.88 | MEN1 (0.81) | MEN1KMT2AACHEDRD2CCR5 | |
| SCHEMBL11499121 | 0.86 | MEN1 (0.68) | POLBLMNAMEN1KMT2AACHE | |
| SCHEMBL7966838 | 0.86 | DRD2 (0.58) | POLBLMNAMEN1KMT2AACHE | |
| SCHEMBL7571134 | 0.85 | MEN1 (0.88) | MEN1KMT2AACHEBACE1DRD2 | |
| SCHEMBL9070278 | 0.85 | MEN1 (0.67) | MEN1KMT2AACHEDRD2CCR5 | |
| Hydrochloric Acid SCHEMBL11501364 | 0.84 | MEN1 (0.66) | LMNAMEN1KMT2AACHEDRD2 | |
| SCHEMBL29869413 | 0.84 | MEN1 (0.54) | POLBLMNAMEN1KMT2AACHE | |
| SCHEMBL8659907 | 0.84 | MEN1 (0.65) | MEN1KMT2AACHEDRD2CCR5 | |
| SCHEMBL2588250 | 0.84 | MEN1 (0.65) | MEN1KMT2AACHEBACE1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188396-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1980-02-12 | — | — | US | disclosed |
| EP-0007067-A1 | Phenylpiperidine derivatives, processes for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-01-23 | — | — | EP | disclosed |