Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6225818 | 0.86 | MEN1 (0.41) | MEN1KMT2AMAPTHPGDTP53 | |
| SCHEMBL10333744 | 0.86 | MAPT (0.43) | MEN1KMT2AMAPTHPGDTP53 | |
| SCHEMBL20152373 | 0.80 | MAPT (0.36) | MEN1KMT2AMAPTHPGDTP53 | |
| SCHEMBL11453246 | 0.78 | SMN1; SMN2 (0.44) | MEN1KMT2AMAPTHPGDTP53 | |
| SCHEMBL302204 | 0.77 | CSNK2A1 (0.48) | MEN1KMT2AMAPTHPGDLMNA | |
| SCHEMBL21277532 | 0.77 | TP53 (0.39) | MEN1KMT2AMAPTHPGDTP53 | |
| SCHEMBL11470770 | 0.77 | PTPRC (0.40) | KMT2AMAPTHPGDLMNAGAA | |
| SCHEMBL11470437 | 0.77 | RAB9A (0.39) | MEN1KMT2AMAPTHPGDLMNA | |
| SCHEMBL11464060 | 0.77 | NPC1 (0.47) | MAPTHPGDLMNAALOX15ALDH1A1 | |
| SCHEMBL11454006 | 0.76 | KDM4E (0.31) | GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190663-A | Anti-thrombotic 1,2-benzisothiazolin-3-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-26 | — | — | US | disclosed |
| US-4156729-A | ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |