Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11471867 | 0.88 | HDAC6 (0.48) | HDAC3HDAC1HDAC2HDAC6LMNA | |
| SCHEMBL11463275 | 0.87 | KMT2A (0.49) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL11460277 | 0.82 | L3MBTL1 (0.45) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL21130651 | 0.78 | LMNA (0.55) | KMT2AMAPTMEN1L3MBTL1LMNA | |
| SCHEMBL1676660 | 0.78 | LMNA (0.55) | KMT2AMAPTMEN1L3MBTL1LMNA | |
| SCHEMBL11429228 | 0.77 | MAPT (0.50) | KMT2AMAPTMEN1L3MBTL1LMNA | |
| SCHEMBL11455099 | 0.77 | KMT2A (0.42) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL11461135 | 0.77 | HDAC3 (0.63) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL8686574 | 0.76 | MAPT (0.49) | KMT2AMAPTMEN1L3MBTL1LMNA | |
| SCHEMBL4250581 | 0.76 | KMT2A (0.58) | KMT2AMAPTMEN1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013143-A2 | Substituted anilinopyrimidines, compositions and use thereof as herbicides, processes for their preparation and intermediates for use therein | ICI AUSTRALIA LIMITED (AU) | 1980-07-09 | — | — | EP | disclosed |