Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454422 | 0.87 | HDAC3 (0.50) | KMT2AMAPTL3MBTL1MEN1HDAC3 | |
| SCHEMBL11158124 | 0.83 | KMT2A (0.52) | KMT2AMAPTL3MBTL1MEN1EPHX2 | |
| SCHEMBL11432328 | 0.83 | L3MBTL1 (0.48) | KMT2AMAPTL3MBTL1MEN1EPHX2 | |
| SCHEMBL18331472 | 0.78 | MEN1 (0.58) | KMT2AMAPTL3MBTL1MEN1EPHX2 | |
| SCHEMBL9285601 | 0.78 | MEN1 (0.58) | KMT2AMAPTL3MBTL1MEN1EPHX2 | |
| SCHEMBL11430304 | 0.77 | MAPT (0.58) | KMT2AMAPTL3MBTL1MEN1LMNA | |
| SCHEMBL11452294 | 0.77 | MEN1 (0.47) | KMT2AMAPTL3MBTL1MEN1HDAC3 | |
| SCHEMBL9450065 | 0.77 | L3MBTL1 (0.71) | KMT2AMAPTL3MBTL1MEN1LMNA | |
| SCHEMBL11455680 | 0.77 | MAPT (0.62) | KMT2AMAPTL3MBTL1MEN1HDAC3 | |
| SCHEMBL8686459 | 0.76 | MAPT (0.55) | KMT2AMAPTL3MBTL1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013143-A2 | Substituted anilinopyrimidines, compositions and use thereof as herbicides, processes for their preparation and intermediates for use therein | ICI AUSTRALIA LIMITED (AU) | 1980-07-09 | — | — | EP | disclosed |