Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11459464 | 0.95 | HDAC6 (0.54) | HDAC6MTNR1BMTNR1ASMN1; SMN2HTT | |
| SCHEMBL11457061 | 0.84 | MTNR1B (0.64) | HDAC6MTNR1BMTNR1AALDH1A1HPGD | |
| SCHEMBL27776760 | 0.82 | KMT2A (0.58) | SMN1; SMN2HTTKMT2ATDP1L3MBTL1 | |
| SCHEMBL373315 | 0.78 | HRH3 (0.61) | HDAC6MTNR1BMTNR1A | |
| SCHEMBL8053648 | 0.75 | KEAP1 (0.71) | HDAC6SMN1; SMN2HTTKMT2AKEAP1 | |
| SCHEMBL974703 | 0.73 | GPR119 (0.55) | L3MBTL1HPGD | |
| SCHEMBL3089467 | 0.73 | HRH3 (0.72) | — | |
| SCHEMBL15092199 | 0.72 | KMT2A (0.51) | SMN1; SMN2HTTKMT2ATDP1L3MBTL1 | |
| SCHEMBL4918460 | 0.71 | HRH3 (0.55) | — | |
| SCHEMBL6071051 | 0.71 | HRH3 (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233217-A | USED AS ANALGESICS, NARCOTIC ANTAGONISTS, AND ANTIHISTAMINES | PENNWALT CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| US-4210749-A | USED AS ANALGESICS, NARCOTIC ANTAGONISTS | PENNWALT CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |