Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5148094 | 0.88 | GAA (0.54) | GAAMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL22617575 | 0.83 | GAA (0.52) | GAAMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL6811627 | 0.79 | L3MBTL1 (0.57) | GAAMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL6811621 | 0.79 | L3MBTL1 (0.57) | GAAMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL28048841 | 0.78 | KMT2A (0.57) | GAAMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL17433641 | 0.78 | KMT2A (0.57) | GAAMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL18598370 | 0.78 | ATM (0.61) | GAAKMT2ARAB9ADRD4SMN1; SMN2 | |
| SCHEMBL27369627 | 0.78 | ATM (0.61) | GAAKMT2ARAB9ADRD4SMN1; SMN2 | |
| SCHEMBL24612581 | 0.77 | CTSL (0.55) | GAAMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL25434186 | 0.77 | CTSL (0.55) | GAAMEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216329-A | FROM B-DICARBONYL COMPOUNDS BY OXIMINATION | PHILIP MORRIS INCORPORATED (US) | 1980-08-05 | — | — | US | disclosed |