Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583584 | 0.93 | SPHK1 (0.52) | SPHK1OPRM1TP53CYP2D6GMNN | |
| SCHEMBL4582995 | 0.86 | — | — | |
| SCHEMBL2026328 | 0.83 | OPRM1 (0.43) | SPHK1SLC15A1OPRM1DPP7DPP8 | |
| SCHEMBL16740665 | 0.82 | TRPV1 (0.39) | SPHK1DPP7DPP8DPP4DPP9 | |
| SCHEMBL15936470 | 0.81 | OPRM1 (0.44) | SPHK1SLC15A1OPRM1DPP7DPP8 | |
| SCHEMBL5702825 | 0.78 | OPRM1 (0.52) | SPHK1OPRM1DPP7TP53CYP2D6 | |
| SCHEMBL21325717 | 0.76 | SPHK1 (0.37) | SPHK1SLC15A1OPRM1CYP3A4CA1 | |
| SCHEMBL721340 | 0.75 | OPRM1 (0.55) | SPHK1OPRM1DPP7TP53CYP2D6 | |
| SCHEMBL1470174 | 0.75 | — | — | |
| Pentane SCHEMBL6882146 | 0.75 | TSHR (0.44) | SPHK1OPRM1LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4223138-A | VAPORIZATION, CONDENSATION, RETARDING FLOW TO REACTION ZONE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-16 | — | — | US | disclosed |