SCHEMBL2026328

SCHEMBL2026328

CCCCC(N)NC(N)CCCC

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.43
ALDH1A1 P00352 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
DNM1 Q05193 2/20 0.39
DPP7 Q9UHL4 3/20 0.39
SLC15A1 P46059 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
SPHK1 Q9NYA1 1/20 0.36
SLC1A3 P43003 1/20 0.35
SLC1A2 P43004 1/20 0.35
SLC1A1 P43005 1/20 0.35
DPP8 Q6V1X1 2/20 0.35
DPP4 P27487 1/20 0.35
DPP9 Q86TI2 1/20 0.35
TP53 P04637 1/20 0.34
LAP3 P28838 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5702825 0.95 OPRM1 (0.52) OPRM1ALDH1A1TDP1DNM1DPP7
SCHEMBL721340 0.92 OPRM1 (0.55) OPRM1DPP7CYP3A4SPHK1SLC1A2
SCHEMBL15936470 0.87 OPRM1 (0.44) OPRM1ALDH1A1TDP1DNM1DPP7
SCHEMBL11456015 0.83 SPHK1 (0.43) OPRM1DPP7SLC15A1CYP3A4CA1
SCHEMBL2024922 0.81 OPRM1 (0.35) OPRM1TSHRSLC1A3SLC1A2SLC1A1
SCHEMBL9845918 0.80
SCHEMBL21235179 0.80
SCHEMBL29007339 0.79 OPRM1 (0.54) OPRM1DPP7CYP3A4CA1SPHK1
SCHEMBL10751730 0.79 OPRM1 (0.54) OPRM1DPP7CYP3A4CA1SPHK1
SCHEMBL8863850 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009027186-A2 HYPERBRANCHED POLYMERS COMPRISING GUANIDINE UNITS BASF SE (DE) 2009-03-05 WO claimed
US-20080306237-A1 Highly Functional, Highly Branched Polyureas BASF AKTIENGESELLSCHAFT (DE) 2008-12-11 US claimed
EP-1716197-B1 HIGHLY FUNCTIONAL, HIGHLY BRANCHED POLYUREAS BASF SE (DE) 2008-10-29 EP claimed
EP-1716197-A1 HIGHLY FUNCTIONAL, HIGHLY BRANCHED POLYUREAS BASF AKTIENGESELLSCHAFT (DE) 2006-11-02 EP claimed
WO-2005075541-A1 HIGHLY FUNCTIONAL, HIGHLY BRANCHED POLYUREAS BASF AKTIENGESELLSCHAFT (DE) 2005-08-18 WO claimed
EP-2225337-B1 USE OF HIGHLY BRANCHED POLYMERS IN POLYMER DISPERSIONS FOR GLOSS COLOURS BASF SE (DE) 2017-08-23 EP disclosed
US-9725554-B2 Dendritic polyurea for solubilizing active substances of low solubility BASF SE (DE) 2017-08-08 US disclosed
US-9238764-B2 Two-component coating compositions BASF SE (DE) 2016-01-19 US disclosed
EP-2691451-B1 TWO-COMPONENT COATING COMPOSITIONS BASF SE (DE) 2015-07-01 EP disclosed
US-8936902-B2 Positive-working imageable elements and method of use EASTMAN KODAK COMPANY (US) 2015-01-20 US disclosed
US-20140341822-A1 Associative Thickeners Based on Hyperbranched Polymers BASF SE (DE) 2014-11-20 US disclosed
US-8846842-B2 Production and use of highly functional, highly branched or hyperbranched polylysines BASF AKTIENGESELLSCHAFT (DE) 2014-09-30 US disclosed
US-20070083030-A1 Highly functional, highly branched polyureas BASF AKTIENGESELLSCHAFT (DE) 2007-04-12 US disclosed
US-7176271-B2 Reacting a bifunctional capped diisocyanate or polyisocyanate with a bifunctional primary and/or secondary amine to eliminate the capping agent; intermolecularly reacting the reaction product; adhesion promoters, thixotropes; paints/varnishes, coatings, adhesives; sealants; castable elastomers; foams BASF AKTIENGESELLSCHAFT (DE) 2007-02-13 US disclosed
EP-1716197-A1 HIGHLY FUNCTIONAL, HIGHLY BRANCHED POLYUREAS BASF AKTIENGESELLSCHAFT (DE) 2006-11-02 EP disclosed
WO-2006084816-A1 HYPERBRANCHED POLYMERS FOR USE AS DEMULSIFIERS FOR CRACKING CRUDE OIL EMULSIONS BASF AKTIENGESELLSCHAFT (DE) 2006-08-17 WO disclosed
EP-1685181-A1 HIGHLY FUNCTIONAL, HIGHLY BRANCHED POLYUREAS BASF AKTIENGESELLSCHAFT (DE) 2006-08-02 EP disclosed
US-20050222360-A1 Method for the production of highly functional, highly branched polyureas BASF AKTIENGESELLSCHAFT (DE) 2005-10-06 US disclosed
WO-2005075541-A1 HIGHLY FUNCTIONAL, HIGHLY BRANCHED POLYUREAS BASF AKTIENGESELLSCHAFT (DE) 2005-08-18 WO disclosed
WO-2005044897-A1 HIGHLY FUNCTIONAL, HIGHLY BRANCHED POLYUREAS BASF AKTIENGESELLSCHAFT (DE) 2005-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140341822-A1 Associative Thickeners Based on Hyperbranched Polymers DSG1, TAF11, UROD OPRM1 3282/4885ALDH1A1 574/4885TDP1 233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.