Sugi Predict

Sugi Predict / Compounds / SCHEMBL1145657

SCHEMBL1145657

SCHEMBL1145657

[CH2]OCc1cccc(C)c1

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 2/20 0.64
▸ MAOB P27338 6/20 0.53
▸ TAAR1 Q96RJ0 2/20 0.50
▸ MAOA P21397 1/20 0.47
▸ ACHE P22303 3/20 0.46
▸ MMP2 P08253 1/20 0.43
▸ MMP9 P14780 1/20 0.43
▸ MMP12 P39900 1/20 0.43
▸ LMNA P02545 1/20 0.42
▸ HRH3 Q9Y5N1 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.41
▸ CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6667381 0.82 IDO1 (0.69) IDO1MAOBTAAR1MAOAACHE
SCHEMBL30253988 0.80 IDO1 (0.67) IDO1MAOBTAAR1MAOAACHE
SCHEMBL12379 0.80 IDO1 (0.67) IDO1MAOBTAAR1MAOAACHE
SCHEMBL3160721 0.79 IDO1 (0.60) IDO1MAOBTAAR1MAOAACHE
SCHEMBL11302792 0.78 IDO1 (0.64) IDO1MAOBTAAR1MAOAACHE
SCHEMBL13187449 0.78 IDO1 (0.64) IDO1MAOBTAAR1MAOAACHE
SCHEMBL402229 0.78 IDO1 (1.00) IDO1MAOBTAAR1
SCHEMBL9842152 0.78 IDO1 (0.64) IDO1MAOBTAAR1MAOAACHE
Fluoride SCHEMBL27638420 0.78 IDO1 (0.64) IDO1MAOBTAAR1MAOAACHE
SCHEMBL28054131 0.78 IDO1 (0.64) IDO1MAOBTAAR1MAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112154167-A Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2020-12-29 — — CN disclosed
CN-111315828-A Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2020-06-19 — — CN disclosed
WO-2020021969-A1 COMPOSITION, CURED PRODUCT, OPTICAL FILTER, AND PRODUCTION METHOD FOR CURED PRODUCT 株式会社ADEKA 2020-01-30 — — WO disclosed
US-7888374-B2 Inhibitors of c-jun N-terminal kinases ABBOTT LABORATORIES (US) 2011-02-15 — — US disclosed
US-7662849-B2 Amidino compounds as cysteine protease inhibitors VIROBAY, INC. (US) 2010-02-16 — — US disclosed
US-7342031-B2 Thiadiazole compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-03-11 — — US disclosed
US-20070293510-A1 Thiadiazole compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED ( A JAPANESE CORPORATION) (JP) 2007-12-20 — — US disclosed
US-7273879-B2 Thiadiazole compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-09-25 — — US disclosed
EP-1761485-A1 AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS Schering AG (DE) 2007-03-14 — — EP disclosed
US-20060287527-A1 Process for producing acrylic acid derivative NIPPON SODA CO., LTD. (JP) 2006-12-21 — — US disclosed
US-20050215578-A1 Thiadiazole compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-09-29 — — US disclosed
US-20050171132-A1 Diaminopyrimidine derivatives as selective growth hormone secrectgogue receptor (GHS-R) antagonists XIN ZHILI (US) 2005-08-04 — — US disclosed
US-20050171131-A1 Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists KOSOGOF CHRISTI (US) 2005-08-04 — — US disclosed
EP-1550661-A1 THIADIAZOLE COMPOUND AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2005-07-06 — — EP disclosed
WO-2005030734-A1 DIAMINOPYRIMIDINE DERIVATIVES AS SELECTIVE GROWTH HORMONE SECRECTGOGUE RECEPTOR (GHS-R) ANTAGONISTS ABBOTT LABORATORIES (US) 2005-04-07 — — WO disclosed
US-20050070712-A1 Pyrimidine derivatives as ghrelin receptor modulators ABBOTT LABORATORIES 2005-03-31 — — US disclosed
WO-2004108661-A1 AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS AXYS PHARMACEUTICALS (US) 2004-12-16 — — WO disclosed
EP-1475374-A1 THIADIAZOLE COMPOUNDS AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-10 — — EP disclosed
US-20040152894-A1 Process for producing acrylic acid derivative NIPPON SODA CO. LTD (JP) 2004-08-05 — — US disclosed
EP-1142857-A1 PROCESSES FOR PRODUCING ACRYLIC ACID DERIVATIVE NIPPON SODA CO., LTD. (JP) 2001-10-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152894-A1 Process for producing acrylic acid derivative OXGR1, GART, HAO2 IDO1 3478/4885MAOB 1828/4885TAAR1 808/4885
US-20050215578-A1 Thiadiazole compounds and use thereof C5, C3AR1, TH IDO1 890/4885MAOB 641/4885TAAR1 91/4885
US-20050171131-A1 Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists GHSR, GIPR, GPR119 IDO1 3469/4885MAOB 1407/4885TAAR1 343/4885
US-20050171132-A1 Diaminopyrimidine derivatives as selective growth hormone secrectgogue receptor (GHS-R) antagonists GHSR, GIPR, GPR119 IDO1 3192/4885MAOB 1634/4885TAAR1 360/4885
US-20050070712-A1 Pyrimidine derivatives as ghrelin receptor modulators GPR119, GIPR, GCGR IDO1 2152/4885MAOB 1941/4885TAAR1 244/4885
US-20070293510-A1 Thiadiazole compounds and use thereof C5, C3AR1, TH IDO1 912/4885MAOB 700/4885TAAR1 103/4885
US-20060287527-A1 Process for producing acrylic acid derivative APEH, HAAO, ASNS IDO1 3753/4885MAOB 2738/4885TAAR1 1645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.