Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | HNF4A | P41235 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274704 | 0.87 | MAPT (0.46) | LMNATNKSPARP1CSNK2A2CSNK2B | |
| SCHEMBL11457288 | 0.82 | NPC1 (0.45) | LMNAMEN1KMT2AMAPTCA1 | |
| SCHEMBL11666642 | 0.82 | TNKS (0.51) | LMNATNKSPARP1CSNK2A2CSNK2B | |
| SCHEMBL11552764 | 0.82 | MAPT (0.43) | LMNATNKSPARP1CSNK2A2CSNK2B | |
| SCHEMBL11457217 | 0.82 | MEN1 (0.46) | MEN1KMT2AMAPTCA1CA2 | |
| SCHEMBL11547143 | 0.81 | HNF4A (0.44) | LMNATNKSPARP1CSNK2A2CSNK2B | |
| SCHEMBL11465464 | 0.81 | TNKS (0.50) | TNKSPARP1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL10759258 | 0.81 | TNKS (0.40) | LMNATNKSPARP1CSNK2A2CSNK2B | |
| SCHEMBL11456591 | 0.80 | TNKS (0.39) | LMNATNKSPARP1CSNK2A2CSNK2B | |
| SCHEMBL11573408 | 0.79 | HNF4A (0.49) | LMNATNKSPARP1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014562-A1 | Pyridazines for use in treating fungal infections, pharmaceutical compositions containing them, and processes for their preparation | Pfizer Limited (GB) | 1980-08-20 | — | — | EP | disclosed |
| US-4212865-A | BACTERICIDES | RIKER LABORATORIES, INC. (US) | 1980-07-15 | — | — | US | disclosed |