Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HNF4A | P41235 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274704 | 0.85 | MAPT (0.46) | TNKSLMNAPARP1CSNK2A2CSNK2B | |
| SCHEMBL11637588 | 0.83 | ALDH1A1 (0.40) | TNKSMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11640222 | 0.83 | FASN (0.42) | TNKSMAPTMEN1KMT2AHNF4A | |
| SCHEMBL11457320 | 0.82 | LMNA (0.47) | TNKSLMNAPARP1CSNK2A2CSNK2B | |
| SCHEMBL11497962 | 0.82 | ALDH1A1 (0.39) | TNKSLMNAPARP1CSNK2A2CSNK2B | |
| SCHEMBL11552764 | 0.80 | MAPT (0.43) | TNKSLMNAPARP1CSNK2A2CSNK2B | |
| SCHEMBL11465464 | 0.79 | TNKS (0.50) | TNKSPARP1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11547143 | 0.79 | HNF4A (0.44) | TNKSLMNAPARP1CSNK2A2CSNK2B | |
| SCHEMBL10759258 | 0.79 | TNKS (0.40) | TNKSLMNAPARP1CSNK2A2CSNK2B | |
| SCHEMBL11623296 | 0.79 | VCAM1 (0.38) | TNKSMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124602-A | OPTIONALLY SUBSTITUTED 3-(CYANOPHENYL)BENZOFURANS | RIKER LABORATORIES, INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4048323-A | Antimicrobial (2-nitro-3-benzofuranyl)-benzoic acids | RIKER LABORATORIES, INC. (US) | 1977-09-13 | — | — | US | disclosed |