Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10759258 | 0.86 | TNKS (0.40) | HNF4AHSP90AA1PTPN1TNKSPARP1 | |
| SCHEMBL11470987 | 0.85 | ABCC4 (0.46) | HNF4AHSP90AA1PTPN1TNKSPARP1 | |
| SCHEMBL11497962 | 0.84 | ALDH1A1 (0.39) | HNF4AHSP90AA1PTPN1TNKSPARP1 | |
| SCHEMBL11549511 | 0.84 | HNF4A (0.42) | HNF4AHSP90AA1ALDH1A1MAPTMEN1 | |
| SCHEMBL7274704 | 0.84 | MAPT (0.46) | HNF4AHSP90AA1PTPN1TNKSPARP1 | |
| SCHEMBL10761966 | 0.82 | MAPT (0.41) | HNF4AHSP90AA1PTPN1CSNK2A2CSNK2B | |
| SCHEMBL11552348 | 0.82 | HNF4A (0.43) | HNF4AHSP90AA1ALDH1A1MAPTLMNA | |
| SCHEMBL11457320 | 0.81 | LMNA (0.47) | HNF4AHSP90AA1PTPN1TNKSPARP1 | |
| SCHEMBL11465464 | 0.81 | TNKS (0.50) | PTPN1TNKSPARP1CSNK2A2CSNK2B | |
| SCHEMBL11666642 | 0.79 | TNKS (0.51) | HNF4AHSP90AA1TNKSPARP1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153716-A | BACTERICIDES | RIKER LABORATORIES, INC. (US) | 1979-05-08 | — | — | US | disclosed |