Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.41 |
| ▸ | FABP7 | O15540 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114404 | 0.80 | KMT2A (0.60) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL12235815 | 0.79 | KMT2A (0.64) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL6182639 | 0.79 | KMT2A (0.64) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL25612527 | 0.76 | KMT2A (0.68) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL3757636 | 0.76 | KMT2A (0.72) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL13613350 | 0.76 | KMT2A (0.72) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL402111 | 0.76 | KMT2A (0.68) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL21332462 | 0.75 | KMT2A (0.66) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL14898524 | 0.74 | KMT2A (0.59) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL178731 | 0.73 | KMT2A (0.57) | KMT2AEPHX2FABP5FABP7CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674020-B2 | Process for preparing polyamides | UNIVERSITY OF LEICESTER (GB) | 2014-03-18 | — | — | US | disclosed |
| US-20120130017-A1 | PROCESS AND NEW COMPOUNDS | UNIVERSITY OF LEICESTER (GB) | 2012-05-24 | — | — | US | disclosed |
| EP-2424921-A2 | NEW PROCESS AND NEW COMPOUNDS | University Of Leicester (GB) | 2012-03-07 | — | — | EP | disclosed |
| WO-2011089393-A1 | DETECTION OF TARGET NUCLEIC ACIDS BASED ON OLIGONUCLEOTIDE HYBRIDIZATION AND CHEMICAL LIGATION | TRILLION GENOMICS LIMITED (GB) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011070333-A2 | PROBES | TRILLION GENOMICS LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |
| WO-2010125382-A2 | NEW PROCESS AND NEW COMPOUNDS | UNIVERSITY OF LEICESTER (GB) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130017-A1 | PROCESS AND NEW COMPOUNDS | PARG, POLI, NPEPPS | KMT2A 507/4885EPHX2 1700/4885FABP5 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.