Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11470412 | 0.88 | KDM4E (0.46) | ALDH1A1KDM4EMAPTPKMMEN1 | |
| SCHEMBL15031157 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTPKMMEN1 | |
| SCHEMBL19690118 | 0.83 | AR (0.56) | ALDH1A1KDM4EMAPTPKMMEN1 | |
| SCHEMBL1253014 | 0.82 | KDM4E (0.54) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11466828 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTPKMMEN1 | |
| SCHEMBL8211259 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTPKMMEN1 | |
| SCHEMBL8214258 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTPKMMEN1 | |
| SCHEMBL8206500 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTPKMMEN1 | |
| SCHEMBL7429885 | 0.75 | KDM4E (0.66) | ALDH1A1KDM4EMAPTPKMMEN1 | |
| SCHEMBL31475465 | 0.73 | LMNA (0.67) | ALDH1A1KDM4EMAPTPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4187310-A | ANTIINFLAMMATORY AGENT, ANALGESICS, ENZYME INHIBITORS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-02-05 | — | — | US | disclosed |
| US-4138490-A | Analgesic compositions containing 1,2-dihydro-2-oxoquinol-4-ylpropionic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-02-06 | — | — | US | disclosed |