Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14194626 | 0.82 | IDO1 (0.46) | IDO1TDP1TP53ALDH1A1TAAR1 | |
| SCHEMBL5352730 | 0.80 | TAAR1 (0.56) | IDO1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL3299248 | 0.79 | PYCR1 (0.47) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL6547406 | 0.79 | TAAR1 (0.48) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL2100606 | 0.78 | IDO1 (0.42) | PYCR1IDO1TDP1TP53TAAR1 | |
| SCHEMBL10039342 | 0.78 | PYCR1 (0.40) | PYCR1IDO1TDP1TP53ALDH1A1 | |
| SCHEMBL5350848 | 0.77 | PYCR1 (0.46) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL168406 | 0.77 | PYCR1 (0.46) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL24073162 | 0.76 | IDO1 (0.41) | IDO1KDM4ETAAR1HTTSMN1; SMN2 | |
| SCHEMBL8587112 | 0.76 | PYCR1 (0.47) | PYCR1IDO1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084824-A | Synthesis method of antidepressant drug, namely voethidine | 万特制药(海南)有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117019156-A | Supported metal cluster catalyst and preparation method thereof | 南京大学 | 2023-11-10 | — | — | CN | claimed |
| CN-118209645-A | Method for detecting 2, 4-dimethylbenzene thiophenol related substances | 重庆药友制药有限责任公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-118084824-A | Synthesis method of antidepressant drug, namely voethidine | 万特制药(海南)有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117924215-A | Synthesis method of vothixetine | 万全万特制药（厦门）有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-115181077-B | Synthesis method of vortioxetine with low impurity content | 安徽峆一药业股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117451878-A | Method for detecting related substances of key intermediate of voathixetine hydrobromide | 山东京卫制药有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-115536610-B | Preparation method of vothixetine | 湖南省湘中制药有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-117024343-A | Near infrared fluorescent probe and preparation method and application thereof | 上海工程技术大学 | 2023-11-10 | — | — | CN | disclosed |
| CN-116103684-A | Preparation method of noble metal atomic layer, noble metal catalytic material and application thereof | 南京工业大学 | 2023-05-12 | — | — | CN | disclosed |
| US-20160164075-A1 | PROCESS FOR PRODUCING AN ACTIVE CATHODE MATERIAL COMPRISING A MIXTURE OF A METAL OXIDE AND A METAL SULFIDE AND USE OF THE ACTIVE CATHODE MATERIAL IN RECHARGEABLE ELECTROCHEMICAL CELLS | BASF SE (DE) | 2016-06-09 | — | — | US | disclosed |
| WO-2002067913-A1 | (Z)-STYRYLBENZYLSULFONES AND PHARMACEUTICAL USES THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2002-09-06 | — | — | WO | disclosed |
| US-20010053832-A1 | Olefin polymerization catalyst and process for producing olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-12-20 | — | — | US | disclosed |
| EP-1134234-A1 | Olefin polymerization catalyst and process for producing olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-09-19 | — | — | EP | disclosed |
| EP-1081167-A1 | Olefin polymerization catalyst and process for producing olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-03-07 | — | — | EP | disclosed |
| US-5420128-A | Pyrimidine derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0503099-A1 | PYRIMIDINE DERIVATIVE, PRODUCTION THEREOF, AND ANDROGEN INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-4203897-A | Penam derivatives | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1980-05-20 | — | — | US | disclosed |
| US-4084049-A | CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-04-11 | — | — | US | disclosed |
| US-3954732-A | BACTERICIDAL PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-05-04 | — | — | US | disclosed |