SCHEMBL3299248

SCHEMBL3299248

Cc1ccc(Cc2ccc(C)cc2C)c(C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 1/20 0.47
TDP1 Q9NUW8 2/20 0.46
TP53 P04637 1/20 0.46
AMY1A P0DUB6 1/20 0.45
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 2/20 0.44
TAAR1 Q96RJ0 1/20 0.43
CYP1A2 P05177 2/20 0.41
CYP2A6 P11509 2/20 0.41
RAB9A P51151 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TNF P01375 1/20 0.41
USP2 O75604 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
CASP1 P29466 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11323610 0.89 TAAR1 (0.43) PYCR1TAAR1RAB9ALMNAHTT
SCHEMBL24158114 0.87 PYCR1 (0.40) PYCR1TDP1TP53AMY1AALDH1A1
SCHEMBL4624112 0.85 PYCR1 (0.42) PYCR1TDP1TP53ALDH1A1KDM4E
SCHEMBL6546220 0.85 RAB9A (0.44) PYCR1KDM4ERAB9AKMT2ALMNA
SCHEMBL6547406 0.83 TAAR1 (0.48) PYCR1TDP1TP53ALDH1A1KDM4E
SCHEMBL15488869 0.83 ALDH1A1 (0.46) PYCR1TDP1TP53AMY1AALDH1A1
SCHEMBL3301748 0.82 CYP3A4 (0.53) RAB9ALMNAHTTSMN1; SMN2TNF
SCHEMBL21323294 0.82 HTT (0.46) TAAR1RAB9ALMNAHTTSMN1; SMN2
SCHEMBL20841678 0.82 TAAR1 (0.40) PYCR1TDP1TP53AMY1AALDH1A1
SCHEMBL16864581 0.82 NR1H2 (0.40) PYCR1TDP1TP53AMY1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492384-B2 Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-07-23 US claimed
US-20090325979-A1 NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-12-31 US claimed
WO-1992016537-A1 ALKYL-AROMATIC DIPHOSPHITES ETHYL CORPORATION (US) 1992-10-01 WO claimed
US-11724978-B2 Method for oxidizing a 1,1,-bis-(3,4-dimethylphenyl)-alkane to 3,3′,4,4′-benzophenone tetracarboxylic acid EVONIK FIBRES GMBH (AT) 2023-08-15 US disclosed
EP-3838883-B1 METHOD FOR OXIDIZING A 1,1-BIS-(3,4-DIMETHYLPHENYL)-ALKANE TO 3,3',4,4'-BENZOPHENONE TETRACARBOXYLIC ACID EVONIK FIBRES GMBH (AT) 2023-07-12 EP disclosed
EP-3838883-A1 A METHOD FOR OXIDIZING A 1,1-BIS-(3,4-DIMETHYLPHENYL)-ALKANE TO 3,3',4,4'-BENZOPHENONE TETRACARBOXYLIC ACID Evonik Fibres GmbH (AT) 2021-06-23 EP disclosed
US-20210179527-A1 METHOD FOR OXIDIZING A 1,1,-BIS-(3,4-DIMETHYLPHENYL)-ALKANE TO 3,3',4,4'-BENZOPHENONE TETRACARBOXYLIC ACID EVONIK FIBRES GMBH (AT) 2021-06-17 US disclosed
EP-3408098-B1 NEGATIVELY-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD EASTMAN KODAK CO (US) 2019-11-06 EP disclosed
EP-3012274-B1 AROMATIC HYDROCARBON FORMALDEHYDE RESIN, MODIFIED AROMATIC HYDROCARBON FORMALDEHYDE RESIN, AND EPOXY RESIN, AND METHOD FOR PRODUCING SAID RESINS MITSUBISHI GAS CHEMICAL CO (JP) 2019-10-23 EP disclosed
US-9725551-B2 Aromatic hydrocarbon formaldehyde resin, modified aromatic hydrocarbon formaldehyde resin and epoxy resin, and method for producing these MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-08-08 US disclosed
US-9725551-B2 Aromatic hydrocarbon formaldehyde resin, modified aromatic hydrocarbon formaldehyde resin and epoxy resin, and method for producing these MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-08-08 US disclosed
US-4886656-A ORGANIC PHOSPHATE LIQUID TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-12-12 US disclosed
US-4867905-A HYDROCARBON SOLVENT BECKMAN INSTRUMENTS, INC. (US) 1989-09-19 US disclosed
EP-0253529-A1 Fluorinated polycyclic compounds ISC CHEMICALS LIMITED (GB) 1988-01-20 EP disclosed
US-4689392-A Highly reactive aromatic hydrocarbon-formaldehyde resin and process for preparing the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1987-08-25 US disclosed
EP-0189377-A2 An agricultural composition with reduced toxicity to fishes and shellfishes Takeda Chemical Industries, Ltd. (JP) 1986-07-30 EP disclosed
US-4601588-A COMPONENT WHICH MELTS AT A PORESCRIBED TEMPERATURE AND CHANGES COLOR, INDICATING FRESHNESS OF FROZEN FOODS MATSUMOTO KOSAN KABUSHIKI KAISHA (JP) 1986-07-22 US disclosed
EP-0058430-B1 DYESTUFF-CONTAINING MICROSCOPIC CAPSULE DISPERSION FOR RECORD MATERIALS MITSUI TOATSU CHEMICALS, Inc. (JP) 1985-12-04 EP disclosed
US-4384871-A Dyestuff-containing microscopic capsule dispersion for record materials MITSUI TOATSU CHEMICALS, INC. (JP) 1983-05-24 US disclosed
EP-0058430-A1 Dyestuff-containing microscopic capsule dispersion for record materials MITSUI TOATSU CHEMICALS, Inc. (JP) 1982-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090325979-A1 NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF CACNA1B, CACNA1C, ORAI1 PYCR1 1753/4885TDP1 4412/4885TP53 4777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.