SCHEMBL5352730

SCHEMBL5352730

Cc1ccc(C)c(CS)c1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.56
IDO1 P14902 1/20 0.44
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
POLB P06746 1/20 0.42
HTT P42858 3/20 0.39
KDM4E B2RXH2 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
AMY1A P0DUB6 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
TP53 P04637 2/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
MAPT P10636 1/20 0.37
TACR1 P25103 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14194626 0.82 IDO1 (0.46) TAAR1IDO1ALDH1A1TDP1AMY1A
SCHEMBL22355713 0.81 TAAR1 (0.63) TAAR1IDO1ALDH1A1TDP1POLB
SCHEMBL1145816 0.80 PYCR1 (0.44) TAAR1IDO1ALDH1A1TDP1HTT
SCHEMBL5252725 0.79 TAAR1 (0.60) TAAR1ALDH1A1TDP1POLBHTT
SCHEMBL9491792 0.79 TAAR1 (0.74) TAAR1ALDH1A1TDP1POLBHTT
SCHEMBL6537098 0.78 IDO1 (0.42) TAAR1IDO1ALDH1A1TDP1AMY1A
SCHEMBL5357592 0.77 TAAR1 (0.58) TAAR1ALDH1A1TDP1POLBHTT
SCHEMBL2090774 0.77 TAAR1 (0.58) TAAR1ALDH1A1TDP1POLBHTT
SCHEMBL269825 0.77 TAAR1 (0.58) TAAR1ALDH1A1TDP1POLBHTT
SCHEMBL29462885 0.77 TAAR1 (0.58) TAAR1ALDH1A1TDP1POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117019156-A Supported metal cluster catalyst and preparation method thereof 南京大学 2023-11-10 CN claimed
US-20230313043-A1 OPTICAL COMPONENT MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
CN-114196146-B Preparation method and application of semiconductor sealing element 上海芯密科技有限公司 2023-05-12 CN disclosed
CN-108431149-B Anti-biofouling coatings based on epoxy resins and amine functional polysiloxanes 陶氏环球技术有限责任公司 2020-11-20 CN disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed
CN-102408327-A Phenylacetic acid compounds DAICEL CHEM 2012-04-11 CN disclosed
WO-2009144584-A1 ANTI-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS MITOLOGICS (FR) 2009-12-03 WO disclosed
EP-1407667-B1 HERBICIDE CONTAINING SUBSTITUTED PYRAZOLE DERIVATIVE AS ACTIVE INGREDIENT SDS BIOTECH CORP (JP) 2007-09-26 EP disclosed
US-7186667-B2 Catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-06 US disclosed
CN-1291976-C Antiretroviral pyridine and quinoline derivatives UNIROYAL CHEM CO INC (US) 2006-12-27 CN disclosed
EP-1081167-A1 Olefin polymerization catalyst and process for producing olefin polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-07 EP disclosed
EP-0945437-A1 Pyrazolyl acrylic acid- and pyrazolyl oximino-acetic acid derivatives, their preparation and their use as fungicides SDS Biotech K.K. (JP) 1999-09-29 EP disclosed
US-5444127-A Urea, thiourea, guanidine derivatives, curing agents for epoxy resins, odorless, low temperature HENKEL CORPORATION (US) 1995-08-22 US disclosed
US-4678804-A PHYTOPATHOGENS CHEVRON RESEARCH COMPANY (US) 1987-07-07 US disclosed
US-4394155-A 2-SULFINYL OR 2-SULFONYL SUBSTITUTED UNIROYAL, INC. (US) 1983-07-19 US disclosed
EP-0014745-B1 CURING AGENT FOR POLYEPOXIDES, CURABLE EPOXY RESIN COMPOSITIONS, HARDENED PRODUCTS THEREFROM AND PROCESS FOR CURING A POLYEPOXIDE DIAMOND SHAMROCK CORPORATION (US) 1983-05-25 EP disclosed
EP-0075827-A2 Polyepoxide curing by polymercaptans plus catalytic co-curing agents DIAMOND SHAMROCK CHEMICALS COMPANY (US) 1983-04-06 EP disclosed
EP-0036638-A2 Herbicidal and plant growth regulant 2-sulfinyl and 2-sulfonyl pyridine N-oxides DIAMOND SHAMROCK CORPORATION (US) 1981-09-30 EP disclosed
EP-0014745-A1 Curing agent for polyepoxides, curable epoxy resin compositions, hardened products therefrom and process for curing a polyepoxide DIAMOND SHAMROCK CORPORATION (US) 1980-09-03 EP disclosed
US-4177173-A INFUSIBLE FILMS, CASTINGS OR ADHESIVES DIAMOND SHAMROCK CORPORATION (US) 1979-12-04 US disclosed