Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 3/20 | 0.60 |
| ▸ | KDM4A | O75164 | 3/20 | 0.60 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.60 |
| ▸ | KDM3B | Q7LBC6 | 3/20 | 0.60 |
| ▸ | HIF1AN | Q9NWT6 | 3/20 | 0.60 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.60 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | PLA2G7 | Q13093 | 15/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733027 | 0.81 | LMNA (0.58) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL10986003 | 0.81 | LMNA (0.58) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL11456512 | 0.79 | LMNA (0.74) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL10655643 | 0.78 | LMNA (0.60) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL7708557 | 0.73 | PLA2G7 (0.64) | LMNAPLA2G7 | |
| SCHEMBL10733172 | 0.71 | LMNA (1.00) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL14486534 | 0.70 | DAO (0.76) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL27787214 | 0.69 | MAOB (0.62) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL7009527 | 0.69 | PLA2G7 (1.00) | PLA2G7 | |
| SCHEMBL10981729 | 0.68 | LMNA (0.55) | KDM6BKDM4AKDM4DHIF1ANKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4218452-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-08-19 | — | — | US | disclosed |
| US-4159329-A | BLOCKING AGENTS, ANTAGONISTS, ANTIHISTAMINES | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-06-26 | — | — | US | disclosed |
| US-4145546-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-03-20 | — | — | US | disclosed |