Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 18/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11450171 | 0.92 | PLA2G7 (0.55) | PLA2G7LMNA | |
| SCHEMBL11449322 | 0.88 | LMNA (0.53) | PLA2G7LMNA | |
| SCHEMBL10655643 | 0.87 | LMNA (0.60) | PLA2G7LMNA | |
| SCHEMBL10653223 | 0.87 | PLA2G7 (0.52) | PLA2G7LMNA | |
| SCHEMBL10735501 | 0.87 | PLA2G7 (0.66) | PLA2G7LMNA | |
| SCHEMBL10618910 | 0.86 | PLA2G7 (0.71) | PLA2G7 | |
| SCHEMBL10651125 | 0.85 | LMNA (0.49) | PLA2G7LMNA | |
| SCHEMBL10652674 | 0.85 | PLA2G7 (0.62) | PLA2G7LMNA | |
| SCHEMBL10653116 | 0.85 | PLA2G7 (0.48) | PLA2G7LMNA | |
| SCHEMBL10652057 | 0.85 | PLA2G7 (0.58) | PLA2G7LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6440965-B1 | Substituted pyrimidine derivatives, their preparation and their use in the treatment of neurodegenerative or neurological disorders of the central nervous system | KRENITSKY PHARMACEUTICALS, INC. | 2002-08-27 | — | — | US | disclosed |
| US-4524071-A | HISTAMINE H2-ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1985-06-18 | — | — | US | disclosed |