Psoralen

Psoralen

SCHEMBL4264885

O=C1C=CC(=O)C=C1.O=c1ccc2cc3ccoc3cc2o1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.86
CYP3A4 P08684 5/20 0.86
KDM4E B2RXH2 5/20 0.86
HSD17B10 Q99714 5/20 0.86
ACHE P22303 4/20 0.86
CYP2A6 P11509 4/20 0.86
CYP2D6 P10635 3/20 0.86
CYP2C19 P33261 3/20 0.86
NFKB1 P19838 2/20 0.86
CYP2C9 P11712 2/20 0.86
GAA P10253 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
MGAM O43451 1/20 0.50
SI P14410 1/20 0.50
PTPN1 P18031 1/20 0.50
MGAM2 Q2M2H8 1/20 0.50
ALDH1A1 P00352 6/20 0.49
HPGD P15428 4/20 0.49
MCL1 Q07820 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Psoralen SCHEMBL2684633 0.93 MAOA (1.00) MAOACYP3A4KDM4EHSD17B10ACHE
Psoralen SCHEMBL17835 0.93 MAOA (1.00) MAOACYP3A4KDM4EHSD17B10ACHE
Psoralen SCHEMBL29503678 0.93 MAOA (1.00) MAOACYP3A4KDM4EHSD17B10ACHE
Psoralen SCHEMBL27405230 0.91 MAOA (0.96) MAOACYP3A4KDM4EHSD17B10ACHE
Psoralen SCHEMBL8707426 0.91 MAOA (0.96) MAOACYP3A4KDM4EHSD17B10ACHE
Psoralen SCHEMBL3647286 0.91 MAOA (0.96) MAOACYP3A4KDM4EHSD17B10ACHE
Psoralen SCHEMBL28036058 0.91 MAOA (0.96) MAOACYP3A4KDM4EHSD17B10ACHE
Psoralen SCHEMBL29165499 0.91 MAOA (0.96) MAOACYP3A4KDM4EHSD17B10ACHE
SCHEMBL11458294 0.87 HSD17B10 (0.89) MAOACYP3A4KDM4EHSD17B10ACHE
Psoralen SCHEMBL4376218 0.86 MAOA (0.86) MAOACYP3A4KDM4EHSD17B10ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8802892-B2 Functionalized phenolic compounds and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-20130281652-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC 2013-10-24 US disclosed
US-8318973-B2 Functionalized sinapic acid and methyl sinapate BEZWADA BIOMEDICAL, LLC (US) 2012-11-27 US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 US disclosed
EP-1951260-A2 FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM Bezwada Biomedical LLC (US) 2008-08-06 EP disclosed
WO-2007053794-A2 FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM COMT, AOX1, UGT1A6 MAOA 72/4885CYP3A4 345/4885KDM4E 1444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.