Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244993 | 0.92 | KDM4E (0.65) | KDM4EALDH1A1LMNAGPR35TDP1 | |
| SCHEMBL11182177 | 0.87 | KDM4E (0.60) | KDM4EALDH1A1LMNAGPR35TDP1 | |
| SCHEMBL11834789 | 0.87 | KDM4E (0.60) | KDM4EALDH1A1LMNAGPR35TDP1 | |
| SCHEMBL11461660 | 0.86 | KDM4E (0.58) | KDM4EALDH1A1MAOAMAOBCA12 | |
| SCHEMBL11827832 | 0.86 | KDM4E (0.58) | KDM4EALDH1A1LMNAGPR35TDP1 | |
| SCHEMBL9847179 | 0.83 | KDM4E (0.67) | KDM4EALDH1A1LMNAGPR35TDP1 | |
| SCHEMBL11339840 | 0.83 | KDM4E (0.60) | KDM4EALDH1A1LMNAGPR35TDP1 | |
| SCHEMBL11843063 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1LMNAGPR35TDP1 | |
| SCHEMBL11058733 | 0.82 | GPR35 (0.58) | KDM4EALDH1A1LMNAGPR35TDP1 | |
| SCHEMBL11240996 | 0.82 | GPR35 (0.79) | KDM4EALDH1A1LMNAGPR35TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4213903-A | Basic amino acid salts of chromones | FISONS LIMITED (GB) | 1980-07-22 | — | — | US | disclosed |
| US-4133889-A | ANAPHYLAXIS ANTAGONISTS | FISONS, LTD. (GB) | 1979-01-09 | — | — | US | disclosed |