Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 1/20 | 0.50 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842829 | 0.89 | PGR (0.45) | P2RY2GPR17PGRALPLALPI | |
| SCHEMBL11458590 | 0.85 | ALPL (0.46) | P2RY2GPR17ALPLALPIPKM | |
| SCHEMBL11585606 | 0.80 | P2RY2 (0.53) | P2RY2GPR17EPAS1PGRSLC22A12 | |
| SCHEMBL17287764 | 0.80 | GPR17 (0.64) | P2RY2GPR17EPAS1ALPLALPI | |
| SCHEMBL11851786 | 0.79 | ALPL (0.48) | P2RY2GPR17PGRALPLALPI | |
| SCHEMBL10925848 | 0.79 | TDP1 (0.47) | GPR17CA1CA2CA9PKM | |
| SCHEMBL11448629 | 0.78 | SMN1; SMN2 (0.50) | GPR17CA1CA2CA9CA12 | |
| SCHEMBL11458302 | 0.78 | GPR17 (0.45) | P2RY2GPR17PGRCA1CA2 | |
| SCHEMBL11448257 | 0.78 | CYP3A4 (0.48) | P2RY2GPR17CA1CA2CA9 | |
| SCHEMBL11448385 | 0.78 | F2 (0.50) | P2RY2GPR17ALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216161-A | 3,4-Diaminophenyl sulfonic acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-08-05 | — | — | US | disclosed |
| US-3996369-A | Anthelmintically active 2-carbalkoxyamino benzimidazolyl-5(6)-sulfonic acid phenyl esters | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |