Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11458760 | 0.89 | P2RY2 (0.50) | PGRCNR2P2RY2GPR17ALPL | |
| SCHEMBL11851786 | 0.84 | ALPL (0.48) | PGRCNR2P2RY2GPR17ALPL | |
| SCHEMBL11841874 | 0.79 | TDP1 (0.56) | ALPLALPICA1CA2CA9 | |
| SCHEMBL11840565 | 0.78 | PGR (0.42) | PGRP2RY2GPR17CA1CA2 | |
| SCHEMBL11089561 | 0.78 | GPR17 (0.43) | PGRP2RY2GPR17CA1CA2 | |
| SCHEMBL11844362 | 0.78 | F2 (0.53) | P2RY2GPR17 | |
| SCHEMBL11843618 | 0.78 | TDP1 (0.49) | PGRP2RY2GPR17 | |
| SCHEMBL11844319 | 0.77 | LMNA (0.49) | PGRCNR2GPR17CA1CA2 | |
| SCHEMBL11458590 | 0.77 | ALPL (0.46) | P2RY2GPR17ALPLALPIP2RX7 | |
| SCHEMBL11850328 | 0.75 | CA1 (0.46) | PGRGPR17CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3996368-A | Anthelmintically active 2-carbalkoxyamino-5(6)-phenyl sulfonyloxy benzimidazoles | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |