Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939467 | 0.82 | L3MBTL1 (0.61) | L3MBTL1KDM4EATMKMT2AIL1R1 | |
| SCHEMBL29094431 | 0.81 | RPS6KA5 (0.41) | L3MBTL1KDM4EATMKMT2AALDH1A1 | |
| SCHEMBL29822336 | 0.80 | IL1R1 (0.60) | L3MBTL1KDM4EATMKMT2AIL1R1 | |
| SCHEMBL18811821 | 0.80 | KDM4E (0.59) | L3MBTL1KDM4EATMKMT2AIL1R1 | |
| SCHEMBL27998179 | 0.80 | IL1R1 (0.60) | L3MBTL1KDM4EATMKMT2AIL1R1 | |
| Biphenyl SCHEMBL28483883 | 0.79 | L3MBTL1 (0.86) | L3MBTL1KDM4EATMKMT2AIL1R1 | |
| SCHEMBL11647327 | 0.78 | LMNA (0.51) | KDM4EKMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL3788697 | 0.78 | L3MBTL1 (0.56) | L3MBTL1KDM4EATMKMT2AIL1R1 | |
| SCHEMBL18803008 | 0.78 | IL1R1 (0.62) | L3MBTL1KDM4EATMKMT2AIL1R1 | |
| SCHEMBL64830 | 0.78 | L3MBTL1 (0.68) | L3MBTL1KDM4EATMKMT2AIL1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204998-A | N-Amino indole derivatives having pharmacological activity | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-05-27 | — | — | US | disclosed |