Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11460209 | 0.81 | L3MBTL1 (0.59) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL13866625 | 0.79 | ATM (0.56) | RPS6KA5RENALDH1A1FGFR1DYRK1A | |
| SCHEMBL12168976 | 0.77 | ATM (0.42) | KMT2ARENALDH1A1FGFR1DYRK1A | |
| SCHEMBL6113842 | 0.76 | ATM (0.49) | KMT2AATMKDM4EL3MBTL1TNF | |
| SCHEMBL12098614 | 0.75 | KDM4E (0.67) | RPS6KA5RENALDH1A1FGFR1DYRK1A | |
| SCHEMBL6113913 | 0.75 | ATM (0.47) | KMT2AATMKDM4EL3MBTL1TNF | |
| SCHEMBL12168987 | 0.75 | KDM4E (0.40) | KMT2ARENALDH1A1FGFR1DYRK1A | |
| SCHEMBL12169022 | 0.75 | KDM4E (0.40) | KMT2ARENALDH1A1FGFR1DYRK1A | |
| SCHEMBL25946455 | 0.74 | ATM (0.42) | KMT2AALDH1A1FGFR1DYRK1AATM | |
| SCHEMBL20308292 | 0.74 | ALDH1A1 (0.46) | RPS6KA5KMT2ARENNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685318-A | Heterocyclic compounds and their use for parasitic diseases | 细胞基因公司 | 2023-09-01 | — | — | CN | claimed |
| CN-116685318-A | Heterocyclic compounds and their use for parasitic diseases | 细胞基因公司 | 2023-09-01 | — | — | CN | disclosed |