Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 6/20 | 0.42 |
| ▸ | THRA | P10827 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10001851 | 0.87 | ALDH1A1 (0.43) | PTPN1ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL10001852 | 0.85 | ALDH1A1 (0.39) | PTPN1PTPN2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL13066070 | 0.85 | ALDH1A1 (0.59) | PTPN1PTPN2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL13066400 | 0.84 | ALDH1A1 (0.38) | PTPN1PTPN2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL28997534 | 0.83 | PTPN1 (0.50) | PTPN1PTPN2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL24949285 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPTL3MBTL1LMNAHCRTR1 | |
| SCHEMBL10001850 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPTL3MBTL1LMNAHCRTR1 | |
| SCHEMBL13066288 | 0.78 | ALDH1A1 (0.52) | PTPN1PTPN2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL30267109 | 0.78 | KDM4E (0.61) | PTPN1PTPN2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL112717 | 0.78 | KDM4E (0.61) | PTPN1PTPN2ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424855-B1 | NEW PHOTOINITIATORS | SIEGWERK DRUCKFARBEN AG & CO KGAA (DE) | 2013-12-25 | — | — | EP | disclosed |
| US-8598249-B2 | Photoinitiators | SIEGWERK DRUCKFARBEN AG & CO. KGAA (DE) | 2013-12-03 | — | — | US | disclosed |
| EP-2424855-A1 | NEW PHOTOINITIATORS | Siegwerk Benelux SA (BE) | 2012-03-07 | — | — | EP | disclosed |
| US-20120046377-A1 | Photoinitiators | SIEGWERK BENELUX SA (BG) | 2012-02-23 | — | — | US | disclosed |
| US-20120046377-A1 | Photoinitiators | SIEGWERK BENELUX SA (BG) | 2012-02-23 | — | — | US | disclosed |
| US-20120046377-A1 | Photoinitiators | SIEGWERK BENELUX SA (BG) | 2012-02-23 | — | — | US | disclosed |
| WO-2010124950-A1 | NEW PHOTOINITIATORS | SIEGWERK BENELUX SA (BE) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010124950-A1 | NEW PHOTOINITIATORS | SIEGWERK BENELUX SA (BE) | 2010-11-04 | — | — | WO | disclosed |
| EP-2246330-A1 | New photoinitiators | Siegwerk Benelux SA (BE) | 2010-11-03 | — | — | EP | disclosed |
| EP-2246330-A1 | New photoinitiators | Siegwerk Benelux SA (BE) | 2010-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046377-A1 | Photoinitiators | PPOX, AAAS, CRY1 | PTPN1 3736/4885PTPN2 2823/4885ALDH1A1 1047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.