SCHEMBL11463262

SCHEMBL11463262

COC(=O)CC(=O)ON1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
TSHR P16473 4/20 0.37
EPHX2 P34913 1/20 0.37
GLA P06280 1/20 0.36
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
HSD17B10 Q99714 2/20 0.34
TET2 Q6N021 1/20 0.33
POLB P06746 1/20 0.33
CYP2D6 P10635 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2950462 0.91 ALDH1A1 (0.35) GAAALDH1A1TDP1POLBMEN1
Water SCHEMBL9419678 0.89 ALDH1A1 (0.34) GAAALDH1A1TDP1POLBMEN1
SCHEMBL6671880 0.84 MGAM (0.31) MGAMGAASIMGAM2MEN1
Ether SCHEMBL9419673 0.84 MGAM (0.37) MGAMGAASIMGAM2TSHR
SCHEMBL28108486 0.83 MGAM (0.44) MGAMGAASIMGAM2EPHX2
SCHEMBL10540741 0.81 SMN1; SMN2 (0.36) GAAALDH1A1POLBMEN1CYP1A2
SCHEMBL11452202 0.80 GLA (0.53) TSHRGLAALDH1A1TDP1HSD17B10
SCHEMBL762068 0.78 L3MBTL1 (0.35) GAAALDH1A1TDP1POLBMEN1
SCHEMBL5874140 0.78 ALDH1A1 (0.38) GAATSHRALDH1A1TDP1HSD17B10
Hydrochloric Acid SCHEMBL27501009 0.77 L3MBTL1 (0.35) TSHRALDH1A1TDP1HSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4232152-A POLYURETHANE CATALYSTS AIR PRODUCTS AND CHEMICALS, INC. (US) 1980-11-04 US disclosed
US-4223139-A CATALYSTS FOR POLYURETHANE SYNTHESIS AIR PRODUCTS AND CHEMICALS, INC. (US) 1980-09-16 US disclosed
US-4204062-A CATALYSTS FOR POLYURETHANE SYNTHESIS AIR PRODUCTS & CHEMICALS, INC. (US) 1980-05-20 US disclosed
US-4134994-A CATALYSTS FOR POLYURETHANE SYNTHESIS, EXHIBIT DELAYED ACTION AIR PRODUCTS AND CHEMICALS, INC. (US) 1979-01-16 US disclosed