Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9419678 | 0.98 | ALDH1A1 (0.34) | ALDH1A1MAPTPOLBGAACYP1A2 | |
| SCHEMBL6671880 | 0.92 | MGAM (0.31) | GAAMEN1KMT2A | |
| SCHEMBL11463262 | 0.91 | MGAM (0.39) | ALDH1A1POLBGAACYP1A2MEN1 | |
| SCHEMBL10540741 | 0.89 | SMN1; SMN2 (0.36) | ALDH1A1MAPTPOLBGAACYP1A2 | |
| Ether SCHEMBL9419673 | 0.88 | MGAM (0.37) | ALDH1A1POLBGAACYP1A2MEN1 | |
| SCHEMBL28108486 | 0.87 | MGAM (0.44) | ALDH1A1MAPTGAACYP1A2MEN1 | |
| SCHEMBL5874140 | 0.85 | ALDH1A1 (0.38) | ALDH1A1MAPTPOLBGAACYP1A2 | |
| SCHEMBL3910467 | 0.83 | ALDH1A1 (0.33) | ALDH1A1MAPTPOLBGAACYP1A2 | |
| SCHEMBL3910470 | 0.83 | ALDH1A1 (0.33) | ALDH1A1MAPTPOLBGAACYP1A2 | |
| SCHEMBL5874928 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310771-A | Ultraviolet resistance, hindered amines, metal phosphonates, triazines | PHILLIPS PETROLEUM COMPANY (US) | 1994-05-10 | — | — | US | claimed |
| EP-0567117-A1 | Polyolefin stabilization | PHILLIPS PETROLEUM COMPANY (US) | 1993-10-27 | — | — | EP | claimed |
| US-10364208-B2 | Oxidative coupling of aryl boron reagents with SP3-carbon nucleophiles, and ambient decarboxylative arylation of malonate half-esters via oxidative catalysis | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2019-07-30 | — | — | US | disclosed |
| US-20180186721-A1 | OXIDATIVE COUPLING OF ARYL BORON REAGENTS WITH SP3-CARBON NUCLEOPHILES, AND AMBIENT DECARBOXYLATIVE ARYLATION OF MALONATE HALF-ESTERS VIA OXIDATIVE CATALYSIS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2018-07-05 | — | — | US | disclosed |
| EP-1648867-B1 | PPAR ACTIVE COMPOUNDS | PLEXXIKON INC (US) | 2013-09-04 | — | — | EP | disclosed |
| US-8367828-B2 | PPAR active compounds | PLEXXIKON INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-20120298007-A1 | PROCESS FOR PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZATION PLATE AND DISPLAY UNIT | KONICA MINOLTA OPTO, INC. (JP) | 2012-11-29 | — | — | US | disclosed |
| CN-101326219-B | Method for producing cellulose ester film, polarizing plate, and liquid crystal display device | KONICA MINOLTA OPTO INC | 2012-07-04 | — | — | CN | disclosed |
| WO-2010144959-A1 | ANALOGUES OF ANTI-FIBROTIC AGENTS | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2010-12-23 | — | — | WO | disclosed |
| US-20100210036-A1 | PPAR ACTIVE COMPOUNDS | PLEXXIKON, INC. | 2010-08-19 | — | — | US | disclosed |
| US-7723374-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2010-05-25 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-5310771-A | Ultraviolet resistance, hindered amines, metal phosphonates, triazines | PHILLIPS PETROLEUM COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0567117-A1 | Polyolefin stabilization | PHILLIPS PETROLEUM COMPANY (US) | 1993-10-27 | — | — | EP | disclosed |
| US-4888369-A | CONTAINING SYNERGISTIC MIXTURE OF ADDITIVES | HIMONT INCORPORATED (US) | 1989-12-19 | — | — | US | disclosed |
| US-4198334-A | HEAT, LIGHT, OXIDATION RESISTANCE, PLASTICS | CIBA-GEIGY CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |
| US-4148783-A | HEAT, LIGHT, OXIDATION, AGING RESISTANCE, STABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1979-04-10 | — | — | US | disclosed |
| US-4088496-A | SILVER SALT, DEVELOPER, BINDER AND AN ACTIVATOR, THE ACID PORTION OF WHICH IS 2-CARBOXYCARBOXAMIDE | EASTMAN KODAK COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4060420-A | PHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1977-11-29 | — | — | US | disclosed |
| US-4012260-A | THIAZOLINIUM COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10364208-B2 | Oxidative coupling of aryl boron reagents with SP3-carbon nucleophiles, and ambient decarboxylative arylation of malonate half-esters via oxidative catalysis | SOD1, AOC3, CBR3 | ALDH1A1 862/4885MAPT 3964/4885POLB 176/4885 |
| US-20100210036-A1 | PPAR ACTIVE COMPOUNDS | PPARG, PPARD, PPARA | ALDH1A1 1171/4885MAPT 4598/4885POLB 1093/4885 |
| US-20180186721-A1 | OXIDATIVE COUPLING OF ARYL BORON REAGENTS WITH SP3-CARBON NUCLEOPHILES, AND AMBIENT DECARBOXYLATIVE ARYLATION OF MALONATE HALF-ESTERS VIA OXIDATIVE CATALYSIS | SOD1, AOC3, CBR3 | ALDH1A1 862/4885MAPT 3964/4885POLB 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.