Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LIPE | Q05469 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8683717 | 0.86 | LIPE (0.54) | MAPTLIPELMNATP53CYP1A2 | |
| SCHEMBL8686574 | 0.84 | MAPT (0.49) | MAPTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL9343199 | 0.84 | L3MBTL1 (0.55) | MAPTL3MBTL1LIPELMNATP53 | |
| SCHEMBL9320809 | 0.83 | MEN1 (0.62) | MAPTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL18331472 | 0.81 | MEN1 (0.58) | MAPTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL9285601 | 0.81 | MEN1 (0.58) | MAPTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL163792 | 0.81 | LMNA (0.66) | MAPTLIPELMNANPSR1SCN9A | |
| SCHEMBL30661947 | 0.81 | LMNA (0.66) | MAPTLIPELMNANPSR1SCN9A | |
| SCHEMBL11393861 | 0.80 | HSPB1 (0.57) | MAPTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL8880041 | 0.80 | MAPT (0.77) | MAPTL3MBTL1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712226-A | Optically active D-pyridyloxy phenoxy propionate herbicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-27 | — | — | US | claimed |
| US-4935051-A | POSTEMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4531969-A | Combatting growth of weeds | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| EP-0002800-B1 | Optically active alpha-phenoxypropionic acid dervatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-02 | — | — | EP | disclosed |