SCHEMBL11463560

SCHEMBL11463560

C#CCN1C(=O)N(CO)C(=O)C1C

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
VRK1 Q99986 18/20 0.37
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1461449 0.81 L3MBTL1 (0.42) L3MBTL1
SCHEMBL11461326 0.80 L3MBTL1 (0.33) L3MBTL1
SCHEMBL11460523 0.75 L3MBTL1 (0.37) VRK1L3MBTL1
SCHEMBL11465909 0.72 L3MBTL1 (0.39) VRK1L3MBTL1
SCHEMBL13853142 0.71 L3MBTL1 (0.48) L3MBTL1
SCHEMBL11465799 0.70 L3MBTL1 (0.37) L3MBTL1
SCHEMBL11464542 0.70 ADRA2C (0.33) L3MBTL1
SCHEMBL21531922 0.68 MAOA (0.33)
SCHEMBL8997583 0.67 SMO (0.47) VRK1
SCHEMBL8422483 0.67 SMN1; SMN2 (0.34) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4200758-A 2,4-Imidazolidinedionylmethyl esters and thiolesters of anilino acids ZOECON CORPORATION (US) 1980-04-29 US disclosed